Ambrisentan Medication Information

Learn everything you need to know about Ambrisentan-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Ambrisentan brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Ambrisentan

Pronunciation : am-bree-SEN-tan

ICD Code : Y52.5 Therapeutic Classification : Anti- Hypertensives

Brand Names or Trade Names of Ambrisentan

Endobloc (10mg) | Endobloc (5mg)

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International :

Letairis

Why is Ambrisentan Prescribed? (Indications)

This medication is an endothelin receptor antagonist, prescribed for pulmonary atrial hypertension (high blood pressure in the lungs). The medication blocks the effects of endothelin-1 thereby decreases blood pressure in lungs. The medication also inhibits the thickening of the blood vessel.

When should Ambrisentan not be taken? (Contraindications)

♦ Contraindicated in patients with Idiopathic Pulmonary Fibrosis (IPF), pregnant women and known hypersensitivity. It should not be co-administered with cyclosporine.

What is the dosage of Ambrisentan?

PO- The initial recommended dose is 5mg once daily with or without food. Maximum: 10mg once daily.

How should Ambrisentan be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Ambrisentan?

• Caution should be exercised in patients with history of liver or kidney impairment, decreased sperm count, fluid retention, during breastfeeding.

• Monitor liver function, complete blood count regularly while taking this medication.

What are the side effects of Ambrisentan?

Most common - Peripheral edema, nasal congestion, inflammation of sinuses, flushing, palpitations inflammation of nasopharynx, abdominal pain, nausea, loss of appetite, low fever, itching, constipation and difficulty in breathing.
Central Nervous System- Headache.
Blood- Decrease in hemoglobin level.