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CRi Announces Maestro 2, the Next Generation in Vivo Optical Imaging Systems

Tuesday, November 27, 2007 General News
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WOBURN, Mass., Nov. 26 Cambridge Research &Instrumentation, Inc. (CRi) announces the launch of Maestro 2 optical imagingsystems in North America. The Maestro 2 received widespread acclaim at theboth the recent Society of Molecular Imaging/Academy of Molecular Imagingjoint conference for in vivo imaging, and at the Stanford University SmallAnimal Imaging Workshop as well. Maestro 2, the fully automated version of theaward-winning Maestro small animal imaging system, is the ideal opticalimaging system for both core imaging facilities and individual laboratoriesusing fluorescence-based imaging methodologies.
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Maestro 2 combines the sensitivity and features of the original Maestro invivo imaging system with advanced animal handling features -- an integratedanesthesia system and temperature controlled stage and imaging chamber.Computer-controlled automation through a new, user-friendly interface provideseasy zoom and focus adjustments and a rapid selection of a full range ofexcitation and emission filters. The Flex(TM) liquid crystal tunable filter(LCTF) provides fast, accurate spectral imaging from 500 to 950 nm, coveringthe full range of available in vivo fluorophores. The fully automated systemallows easy instrument setup and calibration for faster, more accurate resultswithin and between experiments. Maestro 2 provides increased sensitivity,automatic removal of autofluorescence for increase spectral contrast, andimproved quantification of experimental results.
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The Flex LCTF technology provides more accurate multiplexing capabilityand better quantification of experimental results. The software includes theReal Component Analysis(TM) (RCA) algorithm for automatic identification ofspectral signatures and the Compute Spectra(TM) tool, which automaticallyseparates combined or overlapping spectral signatures, enabling the end-userto build spectral libraries quickly and to rapidly analyze data. Quantitativemeasurement tools include component segmentation and regions of interest (ROI)analysis. Spatial, temporal and spectral separation of multiple signals areall enabled in the new Maestro 2, resulting in improved detection andquantification of co-localized signals in vivo.

"We are very excited about the Maestro 2 In Vivo Imaging System", saysJames Mansfield, Director of Multispectral Imaging Systems at CRi. "From itsergonomic design, optimized optics and user-friendly software tools, thissystem was designed and developed with the customers' needs in mind."

CRi, a Boston-based biomedical imaging company, has provided innovativeoptical imaging solutions for its customers for more than 20 years. Amultidisciplinary team is dedicated to working with academic and commercialcustomers to provide high-value solutions. CRi provides comprehensive imagingand analysis solutions that enable the user to investigate and characterizebiological phenotypes while preserving spatial context. With over 80 patentsissued and pending, CRi's solution platforms encompass sub-cellular, cellularand whole animal applications. CRi's innovations are being utilized around theworld to enable new breakthroughs in research, health and medicine. For moreinformation visit our website at http://www.cri-inc.com or contact:David Daniels, Ph.D. Director of Marketing CRi 35-B Cabot Road, Woburn, MA 01801 USA Tel: 1-781-935-9099, extension 149 E-mail: [email protected]

SOURCE Cambridge Research & Instrumentation, Inc.
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