The experimental anticancer drug lenvatinib may achieve at least a partial response in thyroid, endometrial, renal cancers and melanoma, phase I clinical studies have indicated.
Thyroid Cancer – Symptoms - Risk Factors - Diagnosis - Treatment - Prevention
“Shaped like a butterfly she sits within the neck,” that’s what an anonymous poet wrote about the thyroid gland but it can become cancerous and spread to other parts.
“Shaped like a butterfly she sits within the neck,” that’s what an anonymous poet wrote about the thyroid gland but it can become cancerous and spread to other parts.
Genetic analysis of the tumor cells identified several mutations that were significantly associated with greater tumor shrinkage and delay of disease progression. Measurements of biochemical markers in patient blood samples also pointed to specific factors linked to the amount of tumor shrinkage following lenvatinib treatment. The researchers propose that these genetic mutations and serum profiles might be useful in identifying patients deriving the greatest benefit from lenvatinib treatment.
The team of researchers contributing to this study is from Eisai Inc., Johns Hopkins University School of Medicine (Baltimore, MD), University of Texas M.D. Anderson Cancer Center (Houston, TX), Centrum Onkologii Instytut of Gliwice (Poland), Fondazione IRCCS Istituto Nazionale del Tumor (Milan, Italy), Azienda Ospedialiera Universitaria Senese (Siena, Italy), Seattle Cancer Care Alliance (Seattle, WA), Royal North Shore Hospital (Leonards, New South Wales, Australia), H. Lee Moffitt Cancer Center (Tampa, FL), Ohio State University School of Medicine (Columbus, OH), University of Arkansas (Little Rock, AR), The Royal Brisbane and Women''s Hospital (Herston, Queensland, Australia), Royal Marsden Hospital (Sutton, UK), and Azienda Ospedaliero Universitaria Pisana (Pisa, Italy) and Institut Gustave Roussy, Villejuif, France.
Screening Tests for Thyroid Dysfunction
High or low thyroid stimulating hormone (TSH) level is indicative of a dysfunctional thyroid.
High or low thyroid stimulating hormone (TSH) level is indicative of a dysfunctional thyroid.
The 81st Annual Meeting of the American Thyroid Association will be held October 26-30, 2011 at the Renaissance Esmeralda Resort & Spa in Indian Wells (near Palm Springs), California. This four day creative and innovative scientific program, chaired by Drs. Anthony Hollenberg and Martha Zeiger, has carefully balanced clinical and basic science sessions on the latest advances in thyroidology. The ATA meeting is designed to offer continuing education for endocrinologists, internists, surgeons, basic scientists, nuclear medicine scientists, pathologists, endocrine fellows and nurses, physician assistants and other health care professionals. Visit www.thyroid.org for more information.
About the ATA
The American Thyroid Association (ATA) is the leading worldwide organization dedicated to the advancement, understanding, prevention, diagnosis and treatment of thyroid disorders and thyroid cancer. ATA is an international individual membership organization with over 1,400 members from 43 countries around the world. Celebrating its 88th anniversary, ATA delivers its mission through several key endeavors: the publication of highly regarded monthly journals, THYROID, Clinical Thyroidology and Clinical Thyroidology for Patients; annual scientific meetings; biennial clinical and research symposia; research grant programs for young investigators, support of online professional, public and patient educational programs; and the development of guidelines for clinical management of thyroid disease. Visit www.thyroid.org for more information.
Advertisement
Hypothyroidism - Causes - Symptoms - Diagnosis - Treatment - FAQs
Symptoms of hypothyroidism are often general, unspecific changes in the body. Lethargy, weight gain, stiffness and cramping of muscles are some of the symptoms of hypothyroidism.
Symptoms of hypothyroidism are often general, unspecific changes in the body. Lethargy, weight gain, stiffness and cramping of muscles are some of the symptoms of hypothyroidism.
Source-Newswise
Hyperthyroidism (Overactive Thyroid) - Causes - Symptoms - Diagnosis - Treatment
Hyperthyroidism is a condition in which the thyroid gland makes excessive thyroid hormone. Grave’s disease is the most common cause of hyperthyroidism.
Hyperthyroidism is a condition in which the thyroid gland makes excessive thyroid hormone. Grave’s disease is the most common cause of hyperthyroidism.
