High Blood Pressure Medications Reduce Risk of Orthostatic Hypotension

Treatment for lower high blood pressure does not increase the risk of developing orthostatic hypotension. On the contrary, lower blood pressure after treatment decreases the risk of orthostatic hypotension.

Medications used for treating high blood pressure also lower the risk of developing orthostatic hypotension. Orthostatic hypotension is characterized by an extreme drop in blood pressure upon standing.

It is an important risk factor for falls, fainting, and death, especially in the vulnerable groups like the elderly, with hypertension.

Diabetes and Hypertension: Preventing a Toxic Combination
Diabetes and hypertension (high blood pressure) are significant health problems worldwide, but like cardiac disease and fatty liver disease, people of Indian origin are disproportionately affected.

‘Treatments that lower blood pressure significantly also help to lower orthostatic hypotension, which is the sudden drop in blood pressure upon standing.’
Read More..

The risk associations of antihypertensive medications with orthostatic hypotension have long been debated. Therefore, many physicians consider orthostatic hypotension as a reason to relax, avoid or de-escalate treatment of high blood pressure.

Researchers at the Beth Israel Deaconess Medical Center (BIDMC), found that treatment for lower high blood pressure did not increase the risk of developing orthostatic hypotension. On the other hand, it decreases the risk of orthostatic hypotension. Therefore, it is not advisable to stop or reduce the use of antihypertensive medication, to reduce the risk of lowering blood pressure on standing up.

Lead investigator Stephen Juraschek, says, "Our findings should challenge the traditional teaching about blood pressure treatment causing orthostatic hypotension, reassuring clinicians about the safety of blood pressure treatment with regard to this condition."

High Blood Pressure | Hypertension - Causes, Symptoms, Diagnosis & Treatment
High blood pressure or hypertension is a chronic condition, which usually lasts a lifetime once it is developed.

Researchers reviewed the health records from nine large clinical trials consisting of 31,043 adults diagnosed with hypertension. Nearly half of the participants were women, one-fourth were over age 75 years, and one in five was African American.

"The study population was diverse, including older adults with a number of chronic conditions associated with cardiovascular disease, including diabetes," said Juraschek.

Five Healthy Lifestyle Modifications that Lower Hypertension Risk
Lifestyle modifications could help in lowering risk of cardiovascular diseases. Find out what possible changes can help you maintain healthy heart.

Around 50% of the patients were treated to either a lower blood pressure goal versus a higher blood pressure goal or with an active drug versus placebo.

The results showed that the risk for low blood pressure upon standing was lower in participants who took medication to lower blood pressure.

Pediatric Hypertension | High Blood Pressure in Children - Causes, Symptoms, Diagnosis, Treatment, Prevention
Pediatric hypertension or high blood pressure in children is usually caused by secondary reasons which need to be investigated and treated.

The greatest decrease in the risk was seen in those with the lowest blood pressure upon standing, compared to those with higher blood pressure on standing.

The second-greatest decrease in risk was seen in participants without diabetes compared to those with diabetes.

The authors concluded that orthostatic hypotension should not be used as a reason to decrease or discontinue blood pressure treatment, because the finding states that more aggressive blood pressure treatment lowered orthostatic hypotension considerably.

The new study is published in Annals of Internal Medicine.

Source-Medindia