It is true that medical technology has improved so much over the recent years. But the risk of having a child with a birth defect continues to be a significant medical problem. About 1 in 33 children are born with structural defects such as malformed limbs, heart problems and facial abnormalities. Patients of all age groups, races, education levels, socioeconomic backgrounds are affected. Birth defects demand a considerable amount of resources in terms of the economy. The problem is however mostly underestimated or rather overlooked by many in the scientific community. An adequate knowledge about the various birth defects and the causes alone can prevent the incidence of birth defects to an extent.