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Health Benefits of Rhubarb

Article Reviewed by Dietitian Julia Samuel, M.Phil on Jul 29, 2020


What is Rhubarb?

Rhubarb (Rheum rhabarbarum) belongs to the family Polygonaceae. It is herbaceous perennial that grows from short, thick rhizomes. The rhubarb stalks get its color owing to the presence of anthocyanins. The shades vary from crimson red, pink to light green.


Interesting Facts about Rhubarb

Rhubarb Nutrition

Rhubarb is a source of vitamin C, vitamin K, calcium, dietary fiber, potassium and manganese.

It also contains polyphenolic flavonoids like �-carotene, zeaxanthin and lutein. Rhubarb also contains, in small amount, B-complex vitamins like folates, niacin, riboflavin, thiamine, vitamin B-6 (pyridoxine) and pantothenic acid.

Health Benefits of Rhubarb

Supports Digestive System

Rhubarb has been used as laxative since ages. Rhubarb contains anthraxquinones compounds including rhein, and emodin and glycosides that give rhubarb its laxative and cathartic properties. Rhubarb aids in weight loss. The dietary fiber in rhubarb promotes healthy digestion and alleviates constipation.

Rhubarb has anti-diarrheal properties. Studies have shown that rhubarb tannins extract significantly decrease the fecal water content in colon and inhibit Aquaporins (AQPs) 2 and 3 expressions to alleviate diarrhea condition. Aquaporins are integral membrane proteins that form pores in the membrane of cells, mainly facilitating transport of water between cells. have a major role in regulating water transfer during diarrhea. Rhubarb is consumed to avoid strain during bowel movements so that pain from hemorrhoids or anal fissures is reduced.

Lethal Blow to Cancer

Rhubarb contains pigment parietin which can suppress 6PGD (6-phosphogluconate dehydrogenase) enzyme, one of the drivers for cancer growth. According to studies it was seen that half of human leukemia cells were killed in 48 hours.

Rhubarb contains quercetin, ferulic acid, resveratrol, anthraquinones and Vitamin C that exhibits strong antioxidant and anti-inflammatory properties. Resveratrol is an aromatase inhibitor, which prevents estrogen-dominant breast cancers. Rhein and emodin are not just laxatives but they help to arrest cancer cell proliferation as well.

Rhubarb consumption helps to reduce stress as it fights inflammation and free radicals.

Reverses Kidney Failure in Diabetics

Diabetic nephropathy (DN) is kidney damage characterized by proliferation of mesangial cell (MC) and excessive accumulation of extracellular matrix (ECM). The treatment involves inhibition of the proliferation of MCs as well as the accumulation of ECM.


Rhubarb contains five free anthraquinones (FARs), including rhein, emodin, aloeemodin, chrysophanol, and physcion. Studies have shown that FARs found in rhubarb can reverse the kidney damage in diabetic patients by arresting the proliferation of MCs and the accumulation of ECM.

Lowers Blood Pressure

Rhubarb contains about 351 mg potassium and 14.6 mg magnesium that helps to relax the muscles and lowers elevated blood pressure. Combined with the benefits of dietary fiber and anthocyanin, rhubarb reduces the risk of heart diseases including heart attack and stroke.

Bone Formation

One cup of rhubarb contains 35.7 mg of vitamin K. It also provides around 8% daily value of calcium. Vitamin-K has an important role in promoting osteoblastic (bone formation and strengthening) activity. Rhubarb helps to maintain bone health. However, the absorption of calcium decreases due to oxalic acid. Regular consumption will help to maintain the ratio of bone resorption and formation. Vitamin K deficiency increases the risk of osteoporosis.

Improves Brain Health

Oxidative stress and free radicals can cause brain damage leading to stroke, Alzheimer's disease. The antioxidant force and vitamins (C, K) present in rhubarb helps to reverse neuronal damage.

Protects Skin & Eyes

The polyphenolic compounds like lutein and zeaxanthin protects the skin and eyes from damages caused by environmental pollution and from free radicals inside the body. Rhubarb helps to keep the vision strong and reduce the risk of developing age-related macular degeneration.

Caveat

Rhubarb is a laxative and long-term use might have few side effects. Consultation with dietitian is vital for long period consumption of rhubarb.


Drug Interactions with Rhubarb

Certain drugs which may interact with Rhubarb should be avoided. Below are mentioned some of the drugs which causes adverse effects.

Recipe

Rhubarb stalks can be roasted. Chopped stalks are added to pies and crumbles. Relish the rhubarb and coconut mousse.

Coconut and Rhubarb Mousse

Ingredients

Method

References:

  1. Rhubarb Tannins Extract Inhibits the Expression of Aquaporins 2 and 3 in Magnesium Sulphate-Induced Diarrhoea Model - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151595/)
  2. Effects of Free Anthraquinones Extract from the Rhubarb on Cell Proliferation and Accumulation of Extracellular Matrix in High Glucose Cultured-Mesangial Cells - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637350/)

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