At some point in their lives, millions of women will develop breast cancer.
![Estrogen Receptor β Limits Tumor Cell Growth and Indicates Outcome Estrogen Receptor β Limits Tumor Cell Growth and Indicates Outcome](https://images.medindia.net/health-images/1200_1000/breast-cancer-gene-mutation.jpg)
In a June 24th study in the Journal of Clinical Investigation, Rong Li and colleagues at the University of Texas determined that activation of the estrogen receptor β (ERβ) limits tumor cell growth. Cancer cells with activated ERβ did not grow well in culture or in mouse models.
Importantly, breast cancer patients that had activated ERβ in breast tissue had increased disease-free survival. This study suggests that ERβ activation may be useful in evaluating the prognosis of breast cancer patients and that treatment strategies that activate ERβ may be useful for cancer therapy.
Source-Eurekalert