H. Pylori Infection may Reduce Risk of Esophageal Allergic Condition

Helicobacter pylori causes infection in the stomach, peptic ulcer but now proves to protect eosinophilic esophagitis, an allergic condition.

The bacteria Helicobacter pylori (H. pylori) which causes infection of the stomach, in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of cases, may help protect against an allergicdisorder of the esophagus condition called eosinophilic esophagitis (EoE).

In a study of 58 adults with EoE and 116 aged- and sex-matched controls, H. pylori infection was inversely associated with EoE. The prevalence of H. pylori in the control group was 37.9%, whereas 3 EoE patients (5.2%) were currently infected with H. pylori and 5 EoE patients (8.6%) reported prior eradication of H. pylori. H. pylori infection was linked with a 76% reduced likelihood of having EoE.

Peptic Ulcer
Encyclopedia section of medindia gives general information about Peptic Ulcer

‘Eosinophilic esophagitis an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell. The symptoms are swallowing difficulty, food impaction, and heartburn.’

"This adds to the evidence that allergic disorders in general may be less common in people with H. pylori infection," said lead author Dr. Ulrike von Aarnim, of the University of Magdeburg, in Germany. The results are published in Alimentary Pharmacology & Therapeutics.

Source-Eurekalert

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