Artificial Intelligence Helps Show How the Brain's Fluids Circulate
Highlights:
- Researchers at the University of Rochester used unique AI techniques to accurately measure brain fluid flow, uncovering new insights into its complexities
- Understanding fluid flow changes in the brain has implications for treating disorders like Alzheimer's, small artery disease, strokes, and traumatic brain injuries
- By combining measurements from animal models and AI technology, researchers generated high-resolution views to reveal pressures, forces, and three-dimensional flow rates
A novel artificial intelligence-based technology for detecting fluid flow around blood vessels in the brain could have significant implications for finding treatments for disorders like Alzheimer's disease. The perivascular gaps that surround cerebral blood arteries convey water-like fluids and aid in waste removal. Fluid flow changes have been associated with neurological disorders such as Alzheimer's, small artery disease, strokes, and traumatic brain injuries, but they are difficult to assess in vivo.
Innovative AI Velocimetry Techniques Unveil Mysteries of Brain Fluid Flow
The University of Rochester Associate Professor Douglas Kelley led a diverse team of mechanical engineers, neuroscientists, and computer scientists in developing unique AI velocimetry techniques to properly determine brain fluid flow. The findings were published in the Proceedings of the National Academy of Sciences (1✔).
"In this study, we combined some measurements from inside the animal models with a novel AI technique that allowed us to effectively measure things that nobody's ever been able to measure before," says Kelley, a faculty member in Rochester's Department of Mechanical Engineering.
Role of AI in Complexities of Brain Fluid Flow
The findings are the result of years of research undertaken by study co-author Maiken Nedergaard, co-director of Rochester's Center for Translational Neuromedicine. Previously, the research was able to perform two-dimensional investigations on fluid flow in perivascular regions by infusing microscopic particles into the fluid and analyzing their position and velocity over time. However, more detailed measurements were required to fully comprehend the system's complexities-and investigating such a crucial, fluid system is difficult.‘Unveiling the mysteries of brain fluid flow! Researchers at @UofR used innovative AI techniques to accurately measure fluid dynamics, opening new doors for understanding neurological disorders. #BrainResearch #ArtificialIntelligence #Neuroscience’
To address this issue, the team teamed with Brown University's George Karniadakis to use artificial intelligence. They used existing 2D data with physics-based neural networks to generate unprecedented high-resolution views of the system.
"This is a way to reveal pressures, forces, and the three-dimensional flow rate with much more accuracy than we can otherwise do," says Kelley. "The pressure is important because nobody knows for sure quite what pumping mechanism drives all these flows around the brain yet. This is a new field."
Reference:
- Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows - (https:www.pnas.org/doi/10.1073/pnas.2217744120)
Cite this Article ⇣⇡
Please use one of the following formats to cite this article in your essay, paper or report:
-
APA
Dr. Trupti Shirole. (2023, June 14). Artificial Intelligence Helps Show How the Brain's Fluids Circulate . Medindia. Retrieved on Dec 04, 2024 from https://www.medindia.net/news/healthwatch/artificial-intelligence-helps-show-how-the-brains-fluids-circulate-212251-1.htm.
MLA
Dr. Trupti Shirole. "Artificial Intelligence Helps Show How the Brain's Fluids Circulate ". Medindia. Dec 04, 2024. <https://www.medindia.net/news/healthwatch/artificial-intelligence-helps-show-how-the-brains-fluids-circulate-212251-1.htm>.
Chicago
Dr. Trupti Shirole. "Artificial Intelligence Helps Show How the Brain's Fluids Circulate ". Medindia. https://www.medindia.net/news/healthwatch/artificial-intelligence-helps-show-how-the-brains-fluids-circulate-212251-1.htm. (accessed Dec 04, 2024).
Harvard
Dr. Trupti Shirole. 2023. Artificial Intelligence Helps Show How the Brain's Fluids Circulate . Medindia, viewed Dec 04, 2024, https://www.medindia.net/news/healthwatch/artificial-intelligence-helps-show-how-the-brains-fluids-circulate-212251-1.htm.