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Marijuana Use Could be a One-Way Ticket to Peripheral Artery Disease

by Dr. Hena Mariam on May 19, 2023 at 5:47 PM
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Highlights:

Marijuana use has progressively increased in recent years. Along with that, studies highlighting the health ailments assosiated with its use have come to light.

A recent study has found a relationship between marijuana use and peripheral artery disease (PAD). Marijuana users have a much higher chance of developing PAD than the overall population, according to the findings.

The Steady Incline of Marijuana and the Decline of the Vascular System

The Centers for Disease Control and Prevention (CDC) has reported that there has been an increase in the use of marijuana with nearly 50 million people reporting using it at least once (1).


While many studies have been conducted to investigate the effects of marijuana use on health, little research has been conducted to investigate the influence of marijuana use on the vascular system.

‘Can the use of marijuana increase the chances of developing peripheral artery disease?’

PAD, a disorder in which restricted arteries reduce blood flow to the arms or legs, affects 6.5 million people in the United States and, if not treated early, can result in loss of mobility, diminished quality of life, heart attack, stroke, and death.

The researchers analyzed de-identified patient data from the National Inpatient Samples (NIS) from 2016 to 2019 who reported marijuana usage and a PAD diagnosis (2).

Patients were further classified depending on whether or not they had undergone any percutaneous lower extremity vascular intervention. The data was evaluated in a binary logistic regression model with SPSS software, a p-value of 0.001 was deemed statistically significant, and samples were normalized for comparison using predicted probabilities.

Marijuana Use can Increase the Risk of Peripheral Artery Disease by ThreeTimes

623,768 of the 30 million patients identified were diagnosed as marijuana users. Patients had an average age of 37.4 years, an even gender distribution, were more likely to be white, and were more likely to be elective admissions.

2,424 of these individuals were also diagnosed with PAD. Marijuana users were more than three times more likely to develop PAD, although there was no statistically significant increase in mortality or need for percutaneous intervention.

"With the increase in marijuana use in the U.S., our findings show that users should be aware of the symptoms of PAD such as leg pain while walking, slower or no hair growth, and feelings of coldness in the leg," said Hirva Vyas, DO, Hackensack University Medical Center, Hackensack, NJ and lead author of the study. "We know PAD is a progressive disease that can dramatically impact the quality of life, making ongoing monitoring of this patient population critical."

According to the study findings, attentive monitoring for disease screening and progression, in addition to cessation counseling, should be undertaken early in the outpatient setting.

References:
  1. Data and Statistics - (https:www.cdc.gov/marijuana/data-statistics.htm)
  2. Marijuana users three times more likely to develop peripheral artery disease - (https:www.eurekalert.org/news-releases/989679)


Source: Medindia

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