Hypertension Drug Delays Ageing
Can an anti-hypertensive drug slow the aging process? The answer is Yes, Rilmenidine commonly used to treat hypertension was found to prolong life span.
Published in Aging Cell, the findings show that animals treated with rilmenidine, currently used to treat hypertension, at young and older ages increases lifespan and improves health markers, mimicking the effects of caloric restriction.
New Drug to Delay Aging
Unlike other drugs previously studied for this purpose by the researchers, the widely-prescribed, oral antihypertensive rilmenidine has potential for future translatability to humans as side-effects are rare and non-severe.‘In C. elegans, the lifespan advantages of rilmenidine therapy were contemplated by the I1-imidazoline receptor nish-1 receptor.’
To date, a caloric restriction diet has been considered the most robust anti-aging intervention, promoting longevity across species. However, studies of caloric restriction in humans have had mixed results and side effects, meaning finding medications like rilmenidine that can mimic the benefits of caloric restriction is the most reasonable anti-aging strategy.
Source: Eurekalert