Learn about the latest research linking insulin and metformin in diabetic foot ulcer exudates, paving the way for innovative treatment approaches
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Insulin and Metformin Interaction in Diabetic Foot Ulcers"
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Insulin and Metformin in Diabetic Foot Ulcers Treatment
Metformin's ability to speed up wound healing could be good news for the 18.6 million people worldwide (1.6 million in the United States) who develop a diabetic foot ulcer, or DFU, in their lifetime.The paper published in ACS Pharmacology and Translational Science explains a previously unknown connection between insulin and metformin in diabetic foot ulcer (DFU) exudates(1✔ ✔Trusted Source
Millions of people with diabetic foot ulcers could benefit from new research discovery
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Researchers at Michigan State University and South Shore Hospital in Massachusetts discovered a link between two popular diabetes medicines, insulin, and metformin, found in diabetic foot ulcer wound exudates, which may promote recovery.
Diabetic Foot Ulcers Exudate
When researchers examined wound exudate (the fluid excreted at the site of an injury), they identified metformin in individuals who took the drug orally, which no one had ever mentioned.Researchers discovered a considerable rise in metformin detected in wounds among people who use both insulin injections and oral metformin. Previously, researchers believed that insulin and metformin did not interact.
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The findings may influence how clinicians approach treating persistent wounds. The combined effects of metformin and insulin, for instance, may be beneficial if a patient sustains a wound.
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Reference:
- Millions of people with diabetic foot ulcers could benefit from new research discovery- (https:humanmedicine.msu.edu/news/2024-millions-of-people-with-diabetic-foot-ulcers-could-benefit-from-new-research-discovery.html)
Source-Eurekalert