New Online Tool for Hearing Loss Research Data Launched
A new online tool that enables easy access to genetic and other molecular data from hundreds of technical research studies involving hearing function and the ear promotes the medical discoveries to reverse hearing loss.
The research portal called gene Expression Analysis Resource (gEAR) developed by University of Maryland School of Medicine (UMSOM) is revealed in the journal Nature Methods.
‘New online research data accessing portal launched to speed up hearing loss innovations.’
It is operated by a group of physician-scientists at the UMSOM Institute for Genome Sciences (IGS) in collaboration with their colleagues at other institutions.
The portal allows researchers to rapidly access the data and provides an easy interpretation of datasets. Scientists can also input their data and compare it to other datasets that help to determine the significance of their new finding.
"It saves scientists a huge amount of time. Instead of relying only on identifying mutations in genes for hearing loss, researchers can easily identify which cells express any gene in the ear, and how this expression changes, for example, as a result of noise exposure or in processes of regeneration in other species" said study corresponding author Ronna Hertzano, MD, PhD, Associate Professor of Otorhinolaryngology-Head & Neck Surgery at UMSOM and founder of the gEAR.
Researchers recently added data from the BRAIN initiative to a specialized domain of the gEAR portal to provide access to those performing neuroscience studies for a better understanding of brain function and neurodegenerative diseases like Alzheimer's.
The portal is free and available to any researcher seeking access. Users of the portal can do a variety of applications depending on their needs.
They can access the dataset uploader and add their dataset into gEAR to view their data in a private setting. This enables them to see their findings in the context of other public data before posting their results online or submitting their paper for publication.
Once a manuscript is published, a permalink can be included in the manuscript which links readers directly to a curated view of that dataset.
Currently, the portal includes over 800 datasets, and has more than 1,200 registered users and over 80 citations in research studies.
This portal not only access allows access to data in large repositories, it also curates and organizes the data into an accessible format so it can be used to address important scientific questions.
The gEAR portal is a beautiful example of the value of close collaboration of clinicians, biologists, and engineers to bridge the gap in technology.
Source: Medindia