Scientists discovered how the cavity-causing microbes present in the mouth invades the heart tissue and causes lethal infection endocarditis.
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There the bacteria can cause the deadly endocarditis, which refers to the inflammation of heart valves.
The findings have raised the possibility of creating a screening tool, like a swab of the cheek or a spit test to gauge a dental patient's vulnerability to the condition.
"When I first learned that S. mutans sometimes can live in the heart, I asked myself: Why in the world are these bacteria, which normally live in the mouth, in the heart? I was intrigued. And I began investigating how they get there and survive there," said Jacqueline Abranches, research assistant professor in the Department of Microbiology and Immunology at the University of Rochester Medical Center.
Researchers have found that a collagen-binding protein known as CNM gives S. mutans its ability to invade heart tissue.
Without the CNM, the bacteria simply couldn't gain a foothold. Their ability to adhere was about one-tenth of what it was with CNM.
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Source-ANI