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Treating Opioid Addiction in Prison Inmates With Drugs Saves Lives

by Dr. Jayashree Gopinath on April 17, 2023 at 11:36 PM
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Opioid addiction in people serving long term in jails and prisons should be treated with medications for opioid use disorder (MOUD) to prevent overdose deaths and save healthcare costs, suggests new research from Boston Medical Center published in JAMA Network Open.


Overdose is the leading cause of accidental death in the US. Medications for opioid use disorder (MOUD) are lifesaving, but only a fraction of people with opioid overdose disorder (OUD) initiate MOUD treatment.

Care for Opioid Use Disorder in the Criminal Justice System

People with addiction are more likely to be incarcerated than treated, with those from communities of color who use drugs more likely to be incarcerated than White people. Most prisons and jails in the United States discontinue medications for opioid use disorder (MOUD) upon incarceration, even if taken stably before incarceration, and do not initiate MOUD before release.

‘Implement comprehensive medications for opioid use disorder (MOUD) programs as part of a suite of state and national policies to combat the opioid epidemic.’

Patients often suffer withdrawal symptoms while incarcerated and the post-incarceration period is a time of very high risk for overdose death. Therefore, offering medications for opioid addiction for incarcerated individuals saves lives.

Specifically, offering all three medications-buprenorphine, methadone, and naltrexone-is the most effective at saving lives and is more cost-effective. This new study hopes to support policy change at the state and federal level, requiring treating opioid use disorder with medications among people who are incarcerated.

Outcomes Associated with Medication Use for Opioid Use Disorder During Incarceration

The study modeled the impact of MOUD access during and upon release from incarceration on population-level overdose mortality and OUD-related treatment costs in Massachusetts using three different strategies: 1) no MOUD provided during incarceration or upon release, 2) offer only extended-release naltrexone (XR-NTX) upon release from incarceration, and 3) offer all three MOUD at intake.

Among 30,000 incarcerated people with OUD, offering no MOUD was associated with 40,927 MOUD treatment starts over 5 years and 1,259 overdose deaths after 5 years. Over 5 years, offering XR-NTX at release led to 10,466 additional treatment starts and 40 fewer overdose deaths.

In comparison, offering all three MOUD at intake led to 11,923 additional treatment starts, compared to offering no MOUD, and 83 fewer overdose deaths. Among everyone with OUD in MA, "XR-NTX only" averted 95 overdose deaths over 5 years-a 0.9% decrease in state-level overdose mortality, while the all-MOUD strategy averted 192 overdose deaths-a 1.8% decrease.

In this simulation modeling study, researchers found that offering any MOUD to incarcerated individuals with OUD would prevent overdose deaths, and offering all three MOUD would prevent more deaths and save money.

Researchers believe that a treatment-based approach is more appropriate than an incarceration-based one for treating addiction. Proactively offering treatment during incarceration can save lives and is a cost-effective health intervention, while also supporting the dignity of people who are incarcerated.



Source: Eurekalert

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