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SGLT2 Inhibitors: An Evolution in Diabetes Mellitus? - Frequently Asked Questions

Medically Reviewed by Dr. Sunil Shroff, MBBS, MS, FRCS (UK), D. Urol (Lond) on Nov 10, 2022


FAQs on SGLT2 Inhibitors: An Evolution in Diabetes Mellitus

1. Which specialist doctor to consult for Diabetes?

You should consult a Diabetologist for Diabetes.

2. How do SGLT2 inhibitors work in diabetes?

SGLT2 inhibitors help eliminate excess blood glucose levels by reducing its reabsorption from the kidney in diabetes.

3. Are SGLT2 inhibitors insulin-dependent?

No, the SGLT2 inhibitors are not insulin-dependent.

4. Do SGLT2 inhibitors cause hypoglycemia?

When prescribed in absence of any other therapies, SGLT2 inhibitors generally do not cause hypoglycemia.

5. What is the difference between SGLT1 and SGLT2?

Both SGLT1 and SGLT2 are proteins that are expressed in the proximal convoluted tubule of the kidneys. While SGLT2 is responsible for over 90% of glucose reabsorption from kidneys, SGLT1 aids in the other 10% of renal glucose reabsorption.

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