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Symptoms and Signs of Brain Metastasis

Medically Reviewed by Dr. Kaushik Bharati, MSc, PhD, FRSPH (London) on Nov 27, 2018


What are the Symptoms and Signs of Brain Metastasis?

Some of the clinical features of brain metastases are:


The region in the brain where the tumor grows, affects the associated side of the body with loss of sensory capabilities or disturbance in gait. More than half of those affected with brain metastasis, display cognitive difficulties and weakness.

References:

  1. Mukherjee S. The Emperor of all Maladies: A Biography of Cancer. London: Fourth Estate, 2011.
  2. Vachani C. All about brain metastases - OncoLink - (https://www.oncolink.org/cancers/brain-tumors/brain-metastasis/all-about-brain-metastases)
  3. Gould J. Breaking down the epidemiology of brain cancer. Nature. 2018; 561: S40-S41. - (https://www.nature.com/articles/d41586-018-06704-7)
  4. Eichler AF, Loeffler JS. Multidisciplinary management of brain metastases. Oncologist. 2007;12(7): 884-98. - (http://theoncologist.alphamedpress.org/content/12/7/884.full)
  5. Hardesty DA, Nakaji P. The current and future treatment of brain metastases. Front Surg. 2016; 3: 30. (DOI:10.3389/fsurg.2016.00030). PMID: 27252942. - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879329/)
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  7. Nivolumab and ipilimumab effective against melanoma that has spread to the brain - National Cancer Institute, National Institutes of Health (NIH), USA - (https://www.cancer.gov/news-events/cancer-currents-blog/2018/melanoma-brain-metastases-nivolumab-ipilimumab)
  8. Shipp S. Structure and function of the cerebral cortex. Curr Biol. 2007; 17(12): PR443-449. - (https://www.cell.com/current-biology/fulltext/S0960-9822(07)01148-7#secsection0015)

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