Symptoms and Signs of Nephrotoxicity

What are the Symptoms and Signs of Nephrotoxicity?

The Symptoms & signs of damage done to the kidney due to the drugs include:

• Shortness of breath
• Excessive fatigue
• Nausea

• Pain or pressure in chest
• Retention of fluid, causing swelling in legs, ankles and feet
• Decreased urine output
• Irregular heartbeat

References:

1. Drug-Induced Nephrotoxicity - (https://www.aafp.org/afp/2008/0915/p743.html)
2. Drug-induced Kidney Diseases - (http://www.japi.org/october2003/R-970.pdf)
3. Drug-Induced Nephrotoxicity and Its Biomarkers - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794522/)
4. Drug-induced renal disorders - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594214/)
5. Pharmacology behind Common Drug Nephrotoxicities - (https://cjasn.asnjournals.org/content/early/2018/04/04/CJN.00150118)
6. Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective - (https://www.ncbi.nlm.nih.gov/pubmed/29939355)
7. Diagnosis, Treatment, and Prevention of Nephrotoxicity of Cancer Therapeutic Agents - (https://www.ncbi.nlm.nih.gov/books/NBK12686/)

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