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Osteogenesis Imperfecta - Causes

Medically Reviewed by The Medindia Medical Review Team on Apr 03, 2008


Osteogenesis Imperfecta - Causes

As yet, medical science has been unable to pinpoint the exact cause of this debilitating condition.


It is usually inherited as an autosomal dominant trait, but autosomal recessive and non-hereditary types of the disease are also known to occur. This disease is also closely related to a peculiar condition called dentinogenesis imperfecta. This is a condition that affects dentin formation in the tooth tissue. Dentin is the second layer present after enamel and protects the pulp, which is the nerve of the tooth.

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