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Gene therapy | Condition | Target cells |
Adenosine deaminase | ADA defeciency | Lymphocytes, bone marrow cells. |
Tumor necrosis factor | Melanoma | Tumor infiltrating lymphocytes, autologous tumor cells. |
Interleukin - 2 | Melanoma, glioblastoma, renal cell cancer | Autologous tumor cells, tumor cells |
Factor IX | Hemophilia B | Autologous skin fibroblasts |
LDL receptor | Hypercholesterolemia | Autologous liver cells |
Histocompatibility locus antigen class –I B7 plus β2-microglobulin | Melanoma, colorectal cancer, renal cell cancer | Tumor cells |
HSV thymidine kinase | Glioblastoma, AIDS, ovarian cancer | Tumor cells – T cells |
Cystic fibrosis transmembrane conductance regulator | Cystic fibrosis | Nasal and airway epithelium |
Multi drug resistance -I | Breast cancer | Blood CD 34+ cells |
Granulocyte-macrophage colony stimulating factor | Melanoma | Tumor cells |
Human CNTF | Amyotrophic lateral sclerosis | Encapsulated transduced and exogenic cells. |
p53 | Head and neck squamous carcinoma | Tumor cells |
Fanconi anemia | Fanconi anemia | Bone marrow cells. |
Interleukin- 1 receptor antagonist | Arthritis | Autologous fibroblasts |
Related Links | |
Gene Therapy Introduction | |
Genetic Counseling |
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