Test : Creatinine kinase
Indications : A Creatine kinase (CK) test is used to diagnose the below diseases (1✔ ✔Trusted Source
Creatine Kinase
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Muscular dystrophy: It causes weakness, breakdown, and loss of skeletal muscle functions.
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Rhabdomyolis: A rapid breakdown of muscle tissues caused by serious injury, muscle disease, or other diseases.
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Heart attack
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Heart damages
A creatine kinase (CK) test may be ordered if you have the below symptoms of muscular disorder (2✔ ✔Trusted Source
About Creatine Kinase (CK)
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Muscle weakness
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Balance issues
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Numbness or tingling
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Muscle pain or cramps
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Dark urine
Physiology : Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme That is present in the heart, skeletal muscle, and a small amount in the brain. When the cells in the skeletal muscles, heart muscles, or brain are damaged, they release CK into the blood. (2✔ ✔Trusted Source
About Creatine Kinase (CK)
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There are three types of CK enzymes:
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CK-MM – Found mostly in skeletal muscles
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CK-MB – Found mostly in heart muscle
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CK-BB – Found mostly in brain tissue
Normal Range : The reference range of CK is 22-334 IU/L for men and 22-199 IU/L for women. It may vary from laboratory to laboratory. (3✔ ✔Trusted Source
Creatine kinase in the U.S. population
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Interpretation : Based on the types of CK enzymes, the test results indicate the below results: (1✔ ✔Trusted Source
Creatine Kinase
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Higher than normal CK-MM enzymes: It may mean you have muscular dystrophy or rhabdomyolis
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Higher than normal CK-MB enzymes: It may mean you have heart muscle inflammation or are having a heart attack
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Higher than normal CK-BB enzymes: It may mean you have had a stroke or brain injury
Other conditions which causes higher CK level may include, (1✔ ✔Trusted Source
Creatine Kinase
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Blood clots
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Prolonged surgery
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Hormonal disorders
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Certain medications
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Infections
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Strenuous exercise
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Seizures
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Connective tissue disorders
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Kidney failure
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Celiac disease
- Shot injections
References:
- Creatine Kinase - (https://medlineplus.gov/lab-tests/creatine-kinase/)
- About Creatine Kinase (CK)
- (https://my.clevelandclinic.org/health/diagnostics/22692-creatine-kinase-ck)
- Creatine kinase in the U.S. population
- (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370787/)
TEST RATE OF CPK
"My mother aged 75 has her report as follows, esr count is 70mm/ist hour blood urea 21mg/dl,serum creatinine-9mg/dl, albumin creatinine ratio 181.8 mg/dl"