Biochemistry Test

Test : Schilling test


Indications : Schilling test is used to diagnose the below conditions (1^✔ ✔Trusted Source
Schilling test

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• Vitamin B12 deficiency
• Pernicious anemia
• Malabsorption

Healthcare provider may recommend the schilling test, if you have the following symptoms (2^✔ ✔Trusted Source
Vitamin B12 Deficiency Anemia

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• Muscle weakness
• Memory loss
• Numbness or tingling sensation
• Nausea
• Loss of appetite
• Weight loss
• Diarrhea
• Lack of energy
• Irritability and depression

Physiology : Vitamin B12 helps in the formation of red blood cells (RBCs), maintenance of the central nervous system, and is important for the overall metabolism. Ingested vitamin B12 combines with the intrinsic factor which is produced by cells in the stomach.

Intrinsic factor is essential for Vitamin B12 absorption from the small intestine. When the vitamin B12 absorption is inadequate, it results in some diseases (3^✔ ✔Trusted Source
Schilling test

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Normal Range : The normal value of schilling test is 160-950 picograms per milliliter (pg/mL) or 118-701 picomoles per liter (pmol/L). Values of less than 160 pg/mL (118 pmol/L) are a possible sign of a vitamin B12 deficiency. Normal values may vary slightly due to different measurements and samples are used in different laboratories (4^✔ ✔Trusted Source
Vitamin B12 level

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Interpretation : Vitamin B12 deficiency may lead to (5^✔ ✔Trusted Source
Vitamin B12 Deficiency

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• Memory loss
• Depression
• Bowel incontinence / urinary incontinence
• Peripheral neuropathy
• Degeneration of spinal cord
• Paralysis
• Erectile dysfunction
• Paranoia and delusions

References:

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