Hematology Test

Cold Hemolysin Test/ Donath-Landsteiner Test/PCH Test/ D-L antibody test, Paroxysmal cold Hemoglobinuria.

Dr. Reeja Tharu

Written by Dr. Reeja Tharu, M.Phil.,Ph.D

Dr. Simi Paknikar

Medically Reviewed by Dr. Simi Paknikar, MD

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Test : Cold Hemolysin Test/ Donath-Landsteiner Test/PCH Test/ D-L antibody test, Paroxysmal cold Hemoglobinuria.

Indications : This test is to detect Paroxysmal Cold Hemoglobinuria (PCH), a condition caused by sensitization of RBC (at temperature less than 30°C) by complement binding IgG biphasic hemolysin.

Normal Range : Negative

Test Method : Observation of Red Cell lysis from patients cold activated serum.

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