Test : Siderocyte Stain/ Hemosiderin Stain/ Iron stain/ Pappenheimer Body stain
Indications : The test is used to identify sideroblastic anemias and hemolytic anemia. Semi-quantitation of marrow iron stores evaluation of iron reserve, assist in the diagnosis of iron deficiency and hemosiderosis.
Physiology : Siderotic granules represent iron not yet incorporated into hemoglobin and occur primarily when there is impaired hemoglobin synthesis. Siderocytes are uncommon in the peripheral blood unless a splenectomy has been performed on the patient, Iron stained of bone marrow is more important in terms of deciding on the cause of anemia.
Normal Range : No siderocytes identified, In bone marrow stainable iron present.
Test Method : Prussian blue reaction.
Related Tests : Iron stain, Bone marrow.