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Adalimumab - Indications, Dosage, Side Effects and Precautions

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Adalimumab Medication Information

Get detailed information on Adalimumab, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Adalimumab provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Adalimumab
Pronunciation : a dal aye' mu mab
ICD Code : Y45.4 Therapeutic Classification : Antirheumatics

Trade Names/Brand Names of Adalimumab

International :


Humira

Why is Adalimumab Prescribed? (Indications)

Adalimumab is prescribed to treat autoimmune disorders such as rheumatoid arthritis, ulcerative colitis, Crohn's disease, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis.

It works by inhibiting a specific cell signal protein that causes inflammation.

When should Adalimumab not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Adalimumab?

SC- The recommended dose is 40mg to 80 mg, every two weeks; it may be increased if needed.
Juvenile Idiopathic Arthritis- 15 kg (33 lbs) to <30 kg (66 lbs): 20 mg every two weeks ≥30 kg (66 lbs): 40 mg every two weeks.

How should Adalimumab be taken?

It comes as a solution to inject under the skin (subcutaneous), by a healthcare provider.

What are the warnings and precautions for Adalimumab?

• It may cause serious infection, which leads to death, contact your healthcare provider immediately if you have any signs of infection such as fever, cough, or flu-like symptoms.

• Perform lab test for tuberculosis before treatment. Monitor every patient for active tuberculosis while taking this medication.

• Tuberculosis treatment should be given prior to this medication.

• In some patients it may develop cancer like lymphoma.

• Caution should be exercised in patients with cancer, multiple sclerosis, heart disease, during pregnancy and breastfeeding.

What are the side effects of Adalimumab?

Serious- Infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body , liver failure, blood clot in the lung, cerebrovascular accident, and cancer.
Most common- Injection site reactions, fever, joint pain, numbness, tingling and swelling in the face, tongue, ankles and lower leg regions, headache, rash, nausea and stomach upset.
Respiratory - Upper respiratory tract infection, asthma, sinusitis and flu syndrome.
Gastrointestinal - Feeling full, loss of appetite, pain in you’re the upper stomach that may spread to the shoulder.
Skin - Redness, rash, itching, bruising and pus filled skin eruptions.
Central Nervous System - Dizziness, confusion and tremor.
Respiratory - Difficulty in breathing.
Heart - Cardiovascular disorder, chest pain and heart attack.
Eye - Vision problems (cataract).
Laboratory Test- High cholesterol in blood, reduced levels of platelets and red cells, blood in urine and increase in the liver enzymes.
Miscellaneous - Accidental injury, back pain, urinary tract infection, weight loss, tiredness and high blood pressure.

What are the other precautions for Adalimumab?

Avoid vaccination while taking this medication.

What are the storage conditions for Adalimumab?

Refrigerate at 36°F to 46°F (2°C to 8°C) in an airtight container. Do not freeze. Do not use if frozen even if it has been thawed. When traveling, store HUMIRA in a cool carrier with an ice pack. Protect from light.

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