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Alglucerase injection - Indications, Dosage, Side Effects and Precautions

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Information about Alglucerase injection

Generic Name : Alglucerase injection
Up-to-date prescription details regarding Alglucerase injection are provided here.

Pronunciation : al-GLOO-ser-ase

Learn the correct pronunciation of the Alglucerase injection, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.6 Therapeutic Classification : Enzymes

Trade Names/Brand Names of Alglucerase injection

International :


Ceredase

Why is Alglucerase injection Prescribed? (Indications)

Alglucerase injection is as an enzyme replacement therapy in patients diagnosed with type I Gaucher’s disease, a genetic disorder with symptoms and signs of anemia or bleeding tendency, liver disorder, and bone disease.

When should Alglucerase injection not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Alglucerase injection?

Adults and children 2 years of age and older.
IV - Initial dosage may be as little as 2.5 units/kg 3 times a week up to 60 units/kg as frequently as once a week or as infrequently as every 4 week.

How should Alglucerase injection be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Alglucerase injection?

• Caution should be exercised in patients with history of prostate cancer, any allergy, children especially less than 10 years old, during pregnancy and breastfeeding.

• Monitor liver function, kidney function, and blood counts regularly while taking this medication.

• Extreme caution needed in children less than 2 years of age.

What are the side effects of Alglucerase injection?

Local - Discomfort, itching, burning, swelling and pus.
Miscellaneous - Fever, abdominal discomfort, nausea, vomiting, fatigue, weakness, headache, swelling in the extremities and diarrhea.

What are the other precautions for Alglucerase injection?

Avoid excess dosage.

What are the storage conditions for Alglucerase injection?

Store it in refrigerator (2 - 8°C).
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