- Aliskiren - (https://www.ncbi.nlm.nih.gov/books/NBK507868/)
- Direct Renin Inhibitor: Aliskiren in Chronic Kidney Disease - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614331/ )
- Tekturna (aliskiren) tablets label - (https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021985s023lbl.pdf )
- Aliskiren - (https://medlineplus.gov/druginfo/meds/a607039.html )
- Nifedipine - (https://medlineplus.gov/druginfo/meds/a684028.html)
- Aliskiren (Tekturna), A Novel Antihypertensive Approach to Inhibition of the Renin-Angiotensin-Aldosterone System - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730067/ )
Information about Aliskiren
Generic Name : AliskirenUp-to-date prescription details regarding Aliskiren are provided here.
Pronunciation : a-lis-KYE-ren
Learn the correct pronunciation of the Aliskiren, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y52.5 Therapeutic Classification : Anti- Hypertensives
Trade Names/Brand Names of Aliskiren
India :
International :
Tekturn
Why is Aliskiren Prescribed? (Indications)
Aliskiren alone or in combination with other drugs used to treat essential or primary hypertension, a form of hypertension that occurs with no identifiable cause. It helps to relax the blood vessels and makes the heart to pump the blood effectively.This medication is a renin inhibitor decreases the substances that lead to high blood pressure.
When should Aliskiren not be taken? (Contraindications)
Contraindicated in patients with angioedema, pregnancy, who are taking cyclosporine and hypersensitivity.Do not use aliskiren with angiotensin receptor blockers (ARBs) and the angiotensin converting enzyme inhibitors (ACEIs)in patients with diabetes.
What is the dosage of Aliskiren?
PO- The usual recommended starting dose is 150 mg once daily. Maximum: 300mg.How should Aliskiren be taken?
It comes as a tablet to take by mouth, with or without food.What are the warnings and precautions for Aliskiren?
• Caution should be exercised in patients with history of gout, heart problems, kidney problems, kidney dialysis, diabetes, stroke, heart attack or kidney transplant, dehydration, low blood volume, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.• It may cause dizziness, lightheadedness or fainting, do not drive a car or operate machinery, get up slowly from bed while taking this medication.
• It may cause dehydration, excessive sweating, vomiting or diarrhea, which leads to low blood pressure and severe allergic reactions; if it is so consult with your doctor.
What are the side effects of Aliskiren?
Gastrointestinal- Diarrhea and indigestion.Central Nervous System- Headache, dizziness, fatigue and epilepsy.
Metabolic- Increased level of liver enzymes, Blood Urea Nitrogen and anemia.
What are the other precautions for Aliskiren?
Monitor blood pressure, blood electrolyte levels and kidney function regularly while taking this medication.Avoid excess dosage.
