- Aliskiren - (https://www.ncbi.nlm.nih.gov/books/NBK507868/)
- Direct Renin Inhibitor: Aliskiren in Chronic Kidney Disease - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614331/ )
- Tekturna (aliskiren) tablets label - (https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021985s023lbl.pdf )
- Aliskiren - (https://medlineplus.gov/druginfo/meds/a607039.html )
- Nifedipine - (https://medlineplus.gov/druginfo/meds/a684028.html)
- Aliskiren (Tekturna), A Novel Antihypertensive Approach to Inhibition of the Renin-Angiotensin-Aldosterone System - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730067/ )
Aliskiren Medication Information
Get detailed information on Aliskiren, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Aliskiren provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Aliskiren Pronunciation : a-lis-KYE-ren ICD Code : Y52.5 Therapeutic Classification : Anti- HypertensivesTrade Names/Brand Names of Aliskiren
India :
International :
Tekturn
Why is Aliskiren Prescribed? (Indications)
Aliskiren alone or in combination with other drugs used to treat essential or primary hypertension, a form of hypertension that occurs with no identifiable cause. It helps to relax the blood vessels and makes the heart to pump the blood effectively.This medication is a renin inhibitor decreases the substances that lead to high blood pressure.
When should Aliskiren not be taken? (Contraindications)
Contraindicated in patients with angioedema, pregnancy, who are taking cyclosporine and hypersensitivity.Do not use aliskiren with angiotensin receptor blockers (ARBs) and the angiotensin converting enzyme inhibitors (ACEIs)in patients with diabetes.
What is the dosage of Aliskiren?
PO- The usual recommended starting dose is 150 mg once daily. Maximum: 300mg.How should Aliskiren be taken?
It comes as a tablet to take by mouth, with or without food.What are the warnings and precautions for Aliskiren?
• Caution should be exercised in patients with history of gout, heart problems, kidney problems, kidney dialysis, diabetes, stroke, heart attack or kidney transplant, dehydration, low blood volume, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.• It may cause dizziness, lightheadedness or fainting, do not drive a car or operate machinery, get up slowly from bed while taking this medication.
• It may cause dehydration, excessive sweating, vomiting or diarrhea, which leads to low blood pressure and severe allergic reactions; if it is so consult with your doctor.
What are the side effects of Aliskiren?
Gastrointestinal- Diarrhea and indigestion.Central Nervous System- Headache, dizziness, fatigue and epilepsy.
Metabolic- Increased level of liver enzymes, Blood Urea Nitrogen and anemia.
What are the other precautions for Aliskiren?
Monitor blood pressure, blood electrolyte levels and kidney function regularly while taking this medication.Avoid excess dosage.