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Apixaban - Indications, Dosage, Side Effects and Precautions

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Information about Apixaban

Generic Name : Apixaban
Up-to-date prescription details regarding Apixaban are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Apixaban

International :


Eliquis

Why is Apixaban Prescribed? (Indications)

This medication is an anticoagulant, which is used for reducing the risk of strokes and blood clots in patients with atrial fibrillation who have no problems with their heart valve (nonvalvular atrial fibrillation).

When should Apixaban not be taken? (Contraindications)

Contraindicated in patients with active pathological bleeding and hypersensitivity. It should not be co-administered with unfractionated heparin (UFH), enoxaparin and dalteparin, fondaparinux, and oral anticoagulants.

What is the dosage of Apixaban?

PO- The recommended dose is 5 mg twice daily.
Decrease dose to 2.5 mg PO BID in following conditions
- while coadministrating strong dual inhibitors.
- age ≥ 80 years
- body weight ≤ 60 kg
- serum creatinine ≥ 1.5 mg/dL

How should Apixaban be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Apixaban?

• Caution should be exercised in patients with history of kidney or liver problems, bleeding problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

• Patients already taking 2.5 mg BID, avoid coadministration with strong dual inhibitors.

• Discontinuing eliquis in patients without adequate continuous anticoagulation increases risk of stroke.

What are the side effects of Apixaban?

The most common side effect is bleeding. Other side effects include bleeding in the stomach, intestines, brain, and eyes; the bleeding may be fatal.

What are the other precautions for Apixaban?

Avoid excess dosage.

What are the storage conditions for Apixaban?

Apixaban should be stored at room temperature between 15 C to 30 C (59 F to 86 F).
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