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Argatroban - Indications, Dosage, Side Effects and Precautions

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Information about Argatroban

Generic Name : Argatroban
Up-to-date prescription details regarding Argatroban are provided here.

Pronunciation : ar-GA-troh-ban

Learn the correct pronunciation of the Argatroban, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Argatroban

International :


Acova

Why is Argatroban Prescribed? (Indications)

This medication is an anticoagulant (thrombin inhibitor) agent prescribed for thrombosis treatment in patients with heparin-induced thrombocytopenia (low platelet levels).

When should Argatroban not be taken? (Contraindications)

Contraindicated in patients with severe bleeding, who are taking metronidazole, disulfiram, or heparin and hypersensitivity.

What is the dosage of Argatroban?

IV- Initial Dosage: An infusion should be started at 25 mcg/kg/min and a bolus of 350 mcg/kg over 3 to 5 minutes. It may be adjusted if needed.

How should Argatroban be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Argatroban?

• Caution should be exercised in patients with history of heart disease, blood disorder, stroke, stomach or intestinal problem, low platelet counts (thrombocytopenia), high blood pressure, liver disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may cause bleeding or bruising, avoid injury.

What are the side effects of Argatroban?

Respiratory- Difficulty in breathing and cough.
Heart- Low blood pressure, heart arrest, nausea and fast heart rate.
Genitourinary- Urinary tract infection and abnormal kidney function.
Gastrointestinal- Diarrhea, vomiting, infection and abdominal pain.
Miscellaneous- Fever, sepsis and stroke.

What are the other precautions for Argatroban?

Avoid excess dosage.

What are the storage conditions for Argatroban?

Store it at room temperature (25°C), and in an airtight container.
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