Avapritinib Medication Information

Get detailed information on Avapritinib, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Avapritinib provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Avapritinib

Pronunciation : A-va-pri-ti-nib

Trade Names/Brand Names of Avapritinib

India :

Ayvakit

Why is Avapritinib Prescribed? (Indications)

This medication is used to treat certain cancers of stomach and bowel called Gastro-intestinal stroma Tumors or GIST. It is also used to treat Mastocytosis. This is a condition, in which immune cells named mast cells, build up under the skin and/or in the bones, intestines and other organs.

It is a kinase inhibitor and is available in various strengths.

When should Avapritinib not be taken? (Contraindications)

Patients allergic to Avapritinib
Pregnant and lactating women

What is the dosage of Avapritinib?

Avapritinib is available as a tablet in strengths:

25 mg
50 mg
100 mg
200 mg
300 mg

For GIST: The recommended dose is 300 mg
For Mastocytosis: The recommended dosage is 200 mg

How should Avapritinib be taken?

Avaptitinib tablets should be taken orally once a day on empty stomach. Do not take the missed dose within 8 hours of the next dose. Do not repeat the dose if vomiting occurs and continue with the next scheduled dose.

What are the side effects of Avapritinib?

General: Fatigue, swelling of lower legs or hands

Gastrointestinal: Nausea, vomiting, decreased appetite, constipation, abdominal pain, diarrhea

Nervous system: dizziness, cognitive impairment-like confusion, getting lost, speech problems, drowsiness, changes in mood and behavior

Skin: Rash, hair color changes

Eye: watery eyes

What are the other precautions for Avapritinib?

Patients with intracranial bleeding should be careful while using avapritinib
Cognitive abnormalities can occur. Depending on abnormalities, dose should be adjusted.
In females of reproductive age and who may get pregnant, proper contraceptives should be used during the treatment and for one week after the last dose is administered.
In males with female partners proper contraceptives should be used during the treatment to prevent pregnancy as the drug can cause fetal harm.