Information about Azacitidine

Generic Name : Azacitidine
Up-to-date prescription details regarding Azacitidine are provided here.

Pronunciation : ay-za-SYE-ti-deen

Learn the correct pronunciation of the Azacitidine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y43.1 Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Azacitidine

Zadine | Zadine

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International :

Vidaza

Why is Azacitidine Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for blood cancer. It slows or stops the growth of cancer cells by killing abnormal cells in the bone marrow.

When should Azacitidine not be taken? (Contraindications)

Contraindicated in patients with advanced liver cancer and hypersensitivity.

What is the dosage of Azacitidine?

SC/IV- First Treatment Cycle: The recommended starting dose is 75 mg/m², daily for 7 days.
Subsequent Treatment Cycles: Cycles should be repeated every 4 weeks. The dose may be increased to 100 mg/m².

How should Azacitidine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein or large muscle.

What are the warnings and precautions for Azacitidine?

• Caution should be exercised in patients with history of kidney or liver problems, any allergy, who are taking other medication, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, fainting, or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Monitor liver, kidney functions, and blood cell counts regularly while taking this medication.

• Avoid contact with people who have infections.

What are the side effects of Azacitidine?

Most Common - Nausea, anemia, decrease in blood cells, vomiting, pyrexia, diarrhea, injection site redness, constipation and skin discoloration.
Blood- Anemia.
Gastrointestinal - Abdominal tenderness, constipation, diarrhea, gum bleeding, loose stools, bleeding of mouth, nausea, vomiting and mouth ulcer.
General - Chest pain, injection site bruising, redness, pain, pigmentation, itching, swelling; lethargy, uneasiness and fever.
Infections - Pneumonia and upper respiratory tract infection.
Metabolic - Loss of appetite.
Musculoskeletal - Joint pain, chest wall pain and muscle pain.
Central Nervous system - Dizziness, headache, anxiety and sleeplessness.
Respiratory - Difficulty in breathing.
Skin - Dry skin, discoloration, redness, rash, scar and hives.
Heart - Blood clot, low blood pressure, and red spots.
♦ Miscellaneous- Tumor lysis syndrome, injection site necrosis and Sweet’s syndrome.