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Bendamustine Hydrochloride - Indications, Dosage, Side Effects and Precautions

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Bendamustine Hydrochloride Medication Information

Learn everything you need to know about Bendamustine Hydrochloride-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Bendamustine Hydrochloride brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Bendamustine Hydrochloride
Pronunciation : BEN-da-MUS-teen HYE-droe-KLOR-ide
ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Brand Names or Trade Names of Bendamustine Hydrochloride

India :

International :


Treanda

Why is Bendamustine Hydrochloride Prescribed? (Indications)

This medication is an alkylating agent, prescribed for chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma (NHL). It kills existing cancer cells and limits new cancer cells growth.

When should Bendamustine Hydrochloride not be taken? (Contraindications)

Contraindicated in patients with severe kidney disease, and hypersensitivity.

What is the dosage of Bendamustine Hydrochloride?

IV- The recommended dose is 100 mg/m² over 30 minutes infusion on Days 1 and 2 of a 28-day cycle, up to 6 cycles.

How should Bendamustine Hydrochloride be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Bendamustine Hydrochloride?

• Caution should be exercised in patients with history of infection, liver or kidney problems, other types of cancer, bone marrow depression, any allergy, who are taking this medications, children during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections.

• Avoid live vaccinations during the treatment period.

• Monitor liver, kidney function, uric acid level, complete blood count, blood chemistry regularly while taking this medication.

What are the side effects of Bendamustine Hydrochloride?

Most Common - Fever, nausea and vomiting, weakness, fatigue, uneasiness, dry mouth, drowsiness, cough, constipation, headache and mouth ulcer.
Heart - Fast heart rate and low blood pressure.
Gastrointestinal - Nausea, vomiting, diarrhea, constipation, mouth ulcer, abdominal pain, indigestion, gastroesophageal reflux disease and dry mouth.
General - Fatigue, fever, chills, swelling in the extremities, weakness, infections, chest pain and injection site pain.
Metabolic - Loss of appetite, dehydration, decreased potassium level in blood and decrease in weight.
Musculoskeletal - Back pain, joint pain, pain in extremity and bone pain.
Central Nervous system - Headache, dizziness, sensory loss, sleeplessness, anxiety and depression.
Respiratory - Cough, difficulty in breathing, wheezing and nose congestion.
Skin - Rash, itching, dry skin, night sweats and acidity.

What are the other precautions for Bendamustine Hydrochloride?

Avoid excess dosage.

What are the storage conditions for Bendamustine Hydrochloride?

Store it in room temperature (25°C).

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