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Bleomycin - Indications, Dosage, Side Effects and Precautions

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Bleomycin Medication Information

Get detailed information on Bleomycin, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Bleomycin provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Bleomycin
Pronunciation : blee oh mye' sin

Trade Names/Brand Names of Bleomycin

India :

International :


Blenoxane.

Why is Bleomycin Prescribed? (Indications)

This medication is an anti – cancer agent, used for the treatment of skin, oral cavity, head and neck cancer. It is also used for lymphomas, cancer of the testis and fluid accumulation in the chest caused by cancer.

When should Bleomycin not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, severe lung disease, during pregnancy and lactation.

What is the dosage of Bleomycin?

The recommended dose is 0.25 to 0.5units/kg (10 to 20 units/m²) once in a week, or twice.

How should Bleomycin be taken?

It comes as a solution for injection, administered into the large muscle, vein or under the skin.

What are the warnings and precautions for Bleomycin?

•Caution needed for patients with history of lung infection, pre-existing lung function impairment, kidney impairment, patients who received radiotherapy, particularly to the thorax.

Regular chest x-rays should be done. Discontinue treatment if chest x-rays show infiltrates.

What are the side effects of Bleomycin?

Respiratory- Difficulty in breathing, lung disease and cracking sound.
Heart- Low blood pressure, cerebral arteritis, stroke, heart attack, Raynaud phenomenon(condition where there is spasm of blood vessels mainly in fingers and toes) and thrombotic microangiopathy, (clot formation in small blood vessels) (with combination chemotherapy).
Central Nervous System- Uneasiness.
Skin- Hair loss, redness, thickening of the skin, darkening of skin, nail changes, itching, rash, skin tenderness, mouth ulcer, stretch marks, blistering and scleroderma-like skin changes.
Gastrointestinal- Loss of appetite and vomiting.
Local- Pain, pain at tumor site and inflammation of veins.
Metabolic- Weight loss.
Miscellaneous- Allergic reactions.

What are the other precautions for Bleomycin?

Avoid excess dosage.
Use a reliable birth control method to prevent pregnancy.

What are the storage conditions for Bleomycin?

Injection: Refrigerate at 2-8°C. Do not freeze it.

Schedule : G
Drugs that are to be used only under medical supervision.

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