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Cabazitaxel - Indications, Dosage, Side Effects and Precautions

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Cabazitaxel Medication Information

Discover comprehensive details about Cabazitaxel, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Cabazitaxel brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Cabazitaxel
Pronunciation : ka-BAZ-i-TAX-el
ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Brand Names or Trade Names of Cabazitaxel

International :


Jevtana

Why is Cabazitaxel Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for prostate cancer with prednisone. It slows or stops the growth of cancer cells.

When should Cabazitaxel not be taken? (Contraindications)

Contraindicated in patients with severe decrease in white blood cells, and hypersensitivity.

What is the dosage of Cabazitaxel?

Dose is based on Body Surface Area (BSA) of the individual.
IV- The recommended dose is 25 mg/m² as a one-hour intravenous infusion every three weeks in combination with oral prednisone 10 mg.

How should Cabazitaxel be taken?

It comes as a solution for injection to be administered by a trained healthcare provider into the vein.

What are the warnings and precautions for Cabazitaxel?

• Caution should be exercised in patients with history of bone marrow depression, poor immunity, decrease in white blood cells, dehydration, kidney or liver disease, infection, stomach problem, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid contact with people who have infections.

• It may reduce platelet counts; avoid injury or bruising.

• Patient may develop with increased risk of kidney damage with the following symptoms: decreased amount of urine, swelling of the face or body. If it is so consult with your doctor.

• Avoid live vaccination during the treatment period.

• Monitor complete blood counts regularly while taking this medication.

What are the side effects of Cabazitaxel?

Blood - Anemia, abnormal decrease in white blood cells and platelets.
Heart - Abnormal heart rhythm and low blood pressure.
Gastrointestinal - Diarrhea, nausea, vomiting, constipation, abdominal pain, and indigestion.
General - Fatigue, weakness, fever, swelling in the extremities, throat inflammation and generalized pain.
Infections - Urinary tract infections.
Metabolic - Loss of appetite, dehydration and decrease in weight.
Musculoskeletal - Back pain, joint pain and muscle spasms.
Central Nervous System - Nerve disease, sensory loss, dizziness, and headache.
Genitourinary - Blood in urine and painful urination.
Respiratory - Difficulty in breathing and cough.
Skin - Hair loss.

What are the other precautions for Cabazitaxel?

Avoid excess dosage.

What are the storage conditions for Cabazitaxel?

Store it at room temperature (25°C), and in an airtight container.

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