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Canakinumab - Indications, Dosage, Side Effects and Precautions

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Canakinumab Medication Information

Learn everything you need to know about Canakinumab-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Canakinumab brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Canakinumab
Pronunciation : KAN-a-KIN-ue-mab
ICD Code : Y43.4 Therapeutic Classification : Monoclonal antibodies

Brand Names or Trade Names of Canakinumab

International :


Ilaris

Why is Canakinumab Prescribed? (Indications)

This medication is an interleukin-1 beta-blocker, prescribed for auto-inflammatory diseases known as cryopyrin-associated periodic syndrome (CAPS). It decreases interleukin-1 beta's activity.

When should Canakinumab not be taken? (Contraindications)

Contraindicated in patients with severe infection, HIV/AIDS, hepatitis B or C, who are taking tumor necrosis factor (TNF) blocker, and known hypersensitivity.

What is the dosage of Canakinumab?

SC- Adult- The recommended dose is 150 mg for patients with body weight greater than 40 kg.
Child- The recommended dose is 15 to 40 kg with an inadequate response; the dose can be increased to 3 mg/kg.

How should Canakinumab be taken?

It comes as a powder for injection (diluted with fluid) to be administered by a healthcare provider under the skin.

What are the warnings and precautions for Canakinumab?

• Caution should be exercised in patients with history of autoimmune disorder, cancer, hepatitis B or C, tuberculosis, infection, flu-like symptoms, any allergy, who are taking other medications, during pregnancy and breast-feeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid contact with people who have infections.

• It should not be used in children less than 4 years old.

What are the side effects of Canakinumab?

Most Common - Diarrhea, influenza, headache and nausea.
Miscellaneous - Increased weight, musculoskeletal pain, fainting, stomach inflammation, nose inflammation, decrease in white blood cells.

What are the other precautions for Canakinumab?

Avoid excess dosage.

What are the storage conditions for Canakinumab?

Store it in refrigerator (2 to 8°C). Do not freeze it.

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