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Dacarbazine - Indications, Dosage, Side Effects and Precautions

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Information about Dacarbazine

Generic Name : Dacarbazine
Up-to-date prescription details regarding Dacarbazine are provided here.

Pronunciation : da kar' ba zeen

Learn the correct pronunciation of the Dacarbazine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Dacarbazine

India :

International :


DTIC-Dome

Why is Dacarbazine Prescribed? (Indications)

This medication is an antineoplastic chemotherapy drug, prescribed for melanoma and Hodgkin's disease. This medication slows the growth and spread of cancer cells in the body.

When should Dacarbazine not be taken? (Contraindications)

Contraindicated in patients with bone marrow suppression and hypersensitivity.

What is the dosage of Dacarbazine?

Malignant Melanoma: The recommended dosage is 2 to 4.5mg/kg/day for 10 days. Treatment may be repeated at 4-week intervals.
Hodgkin's Disease: The recommended dose is 150mg/square meter body surface/day for 5 days.

How should Dacarbazine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Dacarbazine?

• Caution should be exercised in patients with history of liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Avoid drinking alcoholic beverages and citrus fruit juices.

What are the side effects of Dacarbazine?

Most Common - Nausea, vomiting, diarrhea and loss of appetite.
Miscellaneous - Hair loss, tingling, photosensitivity, rashes and facial flushing.
Liver - Liver damage.

What are the other precautions for Dacarbazine?

Avoid excess dosage.

What are the storage conditions for Dacarbazine?

Store it in refrigerator (2-8°C). Do not freeze it.
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