Daclatasvir Medication Information

Learn everything you need to know about Daclatasvir-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Daclatasvir brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Daclatasvir

Brand Names or Trade Names of Daclatasvir

India :

Daklinza

Why is Daclatasvir Prescribed? (Indications)

Daclatasvir belongs to a group of antiviral medications called Hepatitis C virus (NS5A) inhibitors prescribed along with sofosbuvir for the treatment of chronic HCV genotype 3 infection.

The drug mainly works by stopping the hepatitis C virus from multiplying and spreading inside the body.

When should Daclatasvir not be taken? (Contraindications)

Daclatasvir is contraindicated in patients who take medications that can result in faster metabolism of the drug like phenytoin, carbamazepine and rifampicin. It should also be avoided by those who are allergic to the drug, along with other medications and nutrition supplements that could interfere with its effect, and during pregnancy and breast feeding.

What is the dosage of Daclatasvir?

The dose of the drug is 60mg to be taken once daily with food or on an empty stomach along with sofosbuvir for 12 weeks.

How should Daclatasvir be taken?

Daclatasvir comes in the form of a tablet to be taken by mouth with food or on an empty stomach.

What are the warnings and precautions for Daclatasvir?

• Inform your physician before taking the drug if you have had a liver transplant.

• Avoid using the drug if you are planning to become pregnant or are breast feeding.

What are the side effects of Daclatasvir?

General: Weakness, tiredness, headache, nausea, skin rash, diarrhea.
Central Nervous System: Sleep disturbances.
Blood: Anemia

What are the other precautions for Daclatasvir?

• Discontinue the drug if there is any allergic reactions.

What are the Drug Interactions of Daclatasvir?

Daclatasvir should be avoided with:

CYP3A Enzyme Inhibitors
Drugs like clarithromycin, itraconazole, ketoconazole and ritonavir may increase the plasma concentration of daclatasvir.

CYP3A Enzyme Inducers
Drugs like efavirenz, modafinil, dexamethasone may reduce the plasma concentration of daclatasvir.

Anticoagulants
Daclatasvir drug increases the concentration of anticoagulant drug dabigatran when taken together.

Antiarrhythmic Drugs
The combination of daclatasvir, sofosuvir and amiodarone should be avoided since it can cause serious slowing of the heart. This can result in symptoms of dizziness, confusion, problems with memory, chest pain and breathing difficulties. Concomitant administration of daclatasvir with antiarrhythmic drug like digoxin may increase digoxin concentration.

Lipid Lowering Agents
The blood concentration of HMG CoA reductase inhibitors like atorvastatin, rosuvastatin and pravastatin may increase when taken along with daclatasvir.