Deferasirox Medication Information

Learn everything you need to know about Deferasirox-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Deferasirox brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Deferasirox

Pronunciation : de FER a sir ox

Therapeutic Classification : Chelating Agents

Brand Names or Trade Names of Deferasirox

India :

Defrijet (250mg) | Defrijet (500mg) | Desirox (500mg) | Desirox (250mg)

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International :

Exjade

Why is Deferasirox Prescribed? (Indications)

This medication is an iron-chelating agent, prescribed for transfusional hemosiderosis (excess iron due to blood transfusions). It works by attaching to iron in the body so that it can be excreted in feces.

When should Deferasirox not be taken? (Contraindications)

Contraindicated in patients with severe kidney problem, abnormal decrease in platelet counts, bone marrow depression, and hypersensitivity.

What is the dosage of Deferasirox?

PO- The recommended initial daily dose is 20-mg/kg body weight.

How should Deferasirox be taken?

It comes as a tablet to take by mouth, on an empty stomach once a day.

What are the warnings and precautions for Deferasirox?

• Caution should be exercised in patients with history of cancer, blood or bone marrow depression, decrease in platelets, vision problem, hearing problem, infection, dehydration, kidney, liver, or stomach problem, elderly, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Monitor liver and kidney function, blood protein and iron levels, vision, hearing, and complete blood cell counts regularly while taking this medication.

• It may lead to dehydration; drink plenty of fluid to avoid this problem.

What are the side effects of Deferasirox?

Most Common - Abdominal pain, nausea, vomiting, diarrhea and skin rash.
Genitourinary - Presence of protein in urine.
Miscellaneous- Fluid retention, dizziness, anxiety, fever, fatigue, throat pain, hearing loss, and gastrointestinal bleeding.
♦Less Common- Liver failure.