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Dexmedetomidine - Indications, Dosage, Side Effects and Precautions

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Dexmedetomidine Medication Information

Learn everything you need to know about Dexmedetomidine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Dexmedetomidine brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Dexmedetomidine
Pronunciation : dex-MED-e-TO-mi-dine HYE-droe-KLOR-ide
ICD Code : Y47.8 Therapeutic Classification : Sedative-hypnotic Drugs

Brand Names or Trade Names of Dexmedetomidine

India :

International :


Precedex

Why is Dexmedetomidine Prescribed? (Indications)

This medication is a sedative, prescribed for intensive care unit sedation and procedural sedation.

When should Dexmedetomidine not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Dexmedetomidine?

Dosage is based on patient’s condition and response to the medication.
IV: The recommended loading dose is 1mcg/kg over 10 minutes. Maintenance: 0.6mcg to 1mcg/kg/hr.

How should Dexmedetomidine be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Dexmedetomidine?

• A skilled person who has enough knowledge in handling intensive care unit patients should administer this medication.

• Patient may develop with low heart rate, high blood pressure, sinus arrest, if it so either decrease the dosage or stop the medication.

• Caution should be exercised in patients with history of heart diseases, decrease in blood volume, diabetes, chronic high blood pressure, elderly, during pregnancy and lactation.

What are the side effects of Dexmedetomidine?

Most Common- Low blood pressure, slow heart rate and dry mouth.
Body as a Whole - Fever, decreased blood volume, light anesthesia, pain and rigors.
Heart- Blood pressure fluctuation, high/low blood pressure, heart attack, abnormal heart rhythm, fast/slow heart rate and dilation of blood vessels.
Central Nervous System - Dizziness, headache, nerve pain/inflammation, speech disorder, convulsion, anxiety, agitation, confusion, hallucination and illusion.
Gastrointestinal - Abdominal pain, diarrhea, vomiting, nausea and constipation.
Liver- Increased level of liver enzymes and liver damage.
Metabolic- Excess level of acid in blood, increased potassium level in blood and decrease/increase in sugar level.
Blood- Anemia, easy bruising and bleeding.
Genitourinary- Blood urea nitrogen increased and decreased urination.
Respiratory - Asthma, shortness/poor breathing and lung obstruction.
Skin - Increased sweating.
Eye- Abnormal eye sensation and abnormal vision.

What are the other precautions for Dexmedetomidine?

Take full course of treatment.

What are the storage conditions for Dexmedetomidine?

Store it at controlled room temperature (25°C), and in an airtight container.

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