Diphenoxylate and Atropine Medication Information

Discover comprehensive details about Diphenoxylate and Atropine, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Diphenoxylate and Atropine brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Diphenoxylate and Atropine

Pronunciation : AT-row-peen- dye-fen-OX-i-late

ICD Code : Y53.6 Therapeutic Classification : Antidiarrheals

Brand Names or Trade Names of Diphenoxylate and Atropine

International :

Lomotil, Lonox

Why is Diphenoxylate and Atropine Prescribed? (Indications)

This combination medication contains antidiarrheal (a narcotic) and anticholinergic agent, prescribed for diarrhea. Like other narcotics diphenoxylate doesn't have pain- relieving (analgesic) actions,but it reduces bowel activity.

When should Diphenoxylate and Atropine not be taken? (Contraindications)

Contraindicated in patients with jaundice, diarrhea associated with pseudomembranous enterocolitis, and hypersensitivity.

What is the dosage of Diphenoxylate and Atropine?

Adults: The recommended initial dosage is two tablets four times daily or 10 ml liquid four times daily (20 mg per day).

How should Diphenoxylate and Atropine be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Diphenoxylate and Atropine?

• Caution should be exercised in patients with history of electrolyte imbalance, ulcerative colitis, liver or kidney impairment, Down syndrome, numbness, enlarged prostate, urinary obstruction, trouble in urinating, heart diseases, hiatal hernia, asthma, increased eye pressure, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Do not become overheated in hot weather; otherwise it may lead to heatstroke.

What are the side effects of Diphenoxylate and Atropine?

Central Nervous system - Numbness of extremities, emotion, depression, uneasiness, confusion, sedation, drowsiness, dizziness, restlessness, and headache.
Allergic Reactions - Anaphylaxis, fluid retention, hives, swelling of the gums, itching.
Gastrointestinal - Toxic megacolon, paralytic ileus, inflammation of pancreas, vomiting, nausea, and loss of appetite, abdominal discomfort.

What are the other precautions for Diphenoxylate and Atropine?

Avoid excess dosage.

What are the storage conditions for Diphenoxylate and Atropine?

Store the medication as directed by your physician.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.