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Disulfiram - Indications, Dosage, Side Effects and Precautions

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Information about Disulfiram

Generic Name : Disulfiram
Up-to-date prescription details regarding Disulfiram are provided here.

Pronunciation : dye sul' fi ram

Learn the correct pronunciation of the Disulfiram, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y51.1 Therapeutic Classification : Cholinergic Agents

Trade Names/Brand Names of Disulfiram

India :

International :


Antabuse

Why is Disulfiram Prescribed? (Indications)

This medication is an alcohol antagonist, prescribed for chronic alcoholism. It blocks the processing of alcohol in the body.

When should Disulfiram not be taken? (Contraindications)

Contraindicated in patients with severe heart disease, mental disorder, who are taking alcohol containing preparations and hypersensitivity.

What is the dosage of Disulfiram?

Adult: PO- 800 mg as a single dose on the 1st day. Reduce dose by 200 mg/day. Maintenance: 100-200 mg/day.

How should Disulfiram be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Disulfiram?

• Caution should be exercised in patients with history of diabetes, thyroid disease, epilepsy, brain damage, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Monitor liver function and complete blood cell counts regularly while taking this medication.

What are the side effects of Disulfiram?

Eye inflammation, peripheral nerve disease, drowsiness, fatigue, impotence, headache and rash.

What are the other precautions for Disulfiram?

Avoid excess dosage.

What are the storage conditions for Disulfiram?

Store it at room temperature (20° to 25°C) and in an airtight container. Keep away from moisture and heat.
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