Divalproex Medication Information

Learn everything you need to know about Divalproex-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Divalproex brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Divalproex

Pronunciation : dye-VAL-proe-ex

ICD Code : Y46.6 Therapeutic Classification : Anticonvulsants

Brand Names or Trade Names of Divalproex

India :

More info >>>

International :

Depakote

Why is Divalproex Prescribed? (Indications)

This medication is an anticonvulsant, prescribed for bipolar disorder, epilepsy and to prevent migraine headache. It controls the abnormal activity of nerve impulses in the brain and central nervous system.

When should Divalproex not be taken? (Contraindications)

Contraindicated in patients with known hypersensitivity and urea cycle disorder.

What is the dosage of Divalproex?

Adult: PO- Partial seizures; Primary generalized seizures- Initial-10-15 mg/kg/day in 2-4 divided doses. Max: 60 mg/kg/day.
Acute manic episodes of bipolar disorder- Initial- 25 mg/kg once daily. Max: 60 mg/kg/day.
Migraine prophylaxis- 500 mg once daily for 1 wk, up to 1,000 mg once daily.

How should Divalproex be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Divalproex?

• Caution should be exercised in patients with history of brain, liver, kidney problems, metabolic disease, blood disease, decrease in albumin, HIV infection, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

• Avoid alcohol consumption.

• Patient may develop with an increased risk of pancreatic inflammation and suicidal thoughts, if it so consult with your doctor.

What are the side effects of Divalproex?

Most Common- Nausea, vomiting, drowsiness, dizziness, weakness, abdominal pain, indigestion and rash.
Body as a Whole- Chest pain, chills, fever, neck pain and neck rigidity.
Heart- High/low blood pressure, fast heart rate and dilation of blood vessels.
Gastrointestinal- Loss of appetite, fecal incontinence, flatulence, inflammation of gastrointestinal tract/tongue and mouth infection.
Blood- Bruising.
Metabolic - Swelling in the extremities and weight gain.
Musculoskeletal- Joint pain, leg cramps and twitching.
Central Nervous System- Abnormal dreams, abnormal gait, agitation, in-coordination, muscle rigidity, memory loss, sleeplessness, tingling, involuntary movements, abnormal thinking and fainting.
Respiratory - Difficulty in breathing and inflammation of nose.
Skin - Hair loss, skin scar, dry skin, boils, rash, itching and dandruff.
Eye and ENT- Lazy eye, inflammation of eyes, dry eyes, double vision, deafness, ear/eye pain and ringing in the ear.
Genitourinary- Painful menstrual period/urination, urinary incontinence and vaginal inflammation.