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Doxapram - Indications, Dosage, Side Effects and Precautions

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Information about Doxapram

Generic Name : Doxapram
Up-to-date prescription details regarding Doxapram are provided here.

Pronunciation : DOX-uh-pram

Learn the correct pronunciation of the Doxapram, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Therapeutic Classification : Respiratory stimulants

Trade Names/Brand Names of Doxapram

India :

International :


Dopram

Why is Doxapram Prescribed? (Indications)

This medication is a respiratory stimulant, prescribed for airway obstruction and drug induced respiratory depression. It alters neurotransmitters in the brain that stimulate breathing center.

When should Doxapram not be taken? (Contraindications)

Contraindicated in patients with epilepsy, blood clot in lungs, stroke, heart failure, severe high blood pressure and hypersensitivity.

What is the dosage of Doxapram?

Adult: IV- Post-op resp depression- Initial: 0.5-1.5 mg/kg via injection. May repeat hourly if needed. Max total: 4 mg/kg.
Acute resp failure- 1.5-4 mg/min via infusion.

How should Doxapram be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Doxapram?

• Monitor blood pressure, pulse rate, kidney and liver functions regularly while taking this medication.

• Avoid rapid administration; otherwise it will lead to breakdown of blood cells.

• Patient may develop with increased risk of low blood pressure or difficulty in breathing; if so consult with your doctor.

• Caution should be exercised in patients with history of heart, liver or kidney disease, during pregnancy and breastfeeding.

What are the side effects of Doxapram?

Central Nervous Systems- Fever, flushing, tingling, feeling warmth, burning or hot sensation, disorientation, hallucinations, headache, dizziness, hyperactivity, involuntary movements, increased deep tendon reflexes and convulsions.
Respiratory- Difficulty in breathing, increased cough, fast breath and asthma.
Heart- Inflammation of vein, irregular heart rate, chest pain, tightness in chest and high blood pressure.
Gastrointestinal- Nausea, vomiting and diarrhea.
Genitourinary- Uncontrolled urination, urinary retention and elevation of Blood Urea Nitrogen and albumin in urine.
Blood- Breakdown of blood cells, anemia and decrease in white blood cells.
Skin- Sweating and itching.
Eye- Pupil dilation.

What are the other precautions for Doxapram?

Patient must be provided with adequate oxygen and ventilation.
Avoid excess/low dosage.

What are the storage conditions for Doxapram?

Store it at room temperature (20°-25°C) and in an airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
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