Information about Drotrecogin Alfa

Generic Name : Drotrecogin Alfa
Up-to-date prescription details regarding Drotrecogin Alfa are provided here.

Pronunciation : droe-tre-KOE-gin AL-fa

Learn the correct pronunciation of the Drotrecogin Alfa, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Drotrecogin Alfa

Xigris (20 mg) | Xigris

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International :

Xigris Vial

Why is Drotrecogin Alfa Prescribed? (Indications)

This medication is a recombinant form of human activated protein C, prescribed for life-threatening bacterial infections like severe sepsis (sepsis combined with organ malfunction).

When should Drotrecogin Alfa not be taken? (Contraindications)

Contraindicated in patients with high risk of intrinsic bleeding, stroke, epidural catheter, trauma, brain tumor and known hypersensitivity.

What is the dosage of Drotrecogin Alfa?

Adults-Infuse intravenously at 24 mcg/kg/hr (based on actual body weight) for a total duration of 96 hours.

How should Drotrecogin Alfa be taken?

It comes as a solution to be injected by a doctor or hospital staff.

What are the warnings and precautions for Drotrecogin Alfa?

•It may cause severe bleeding, lie down in the bed during the treatment.

• Monitor complete blood count, liver and kidney functions regularly while taking this medication.

• Caution needed for patients with history of kidney disease, liver disease, HIV, organ transplants, stroke, head or spinal surgeries, ulcers, low platelet count, pregnancy, breastfeeding and any form of allergies.

What are the side effects of Drotrecogin Alfa?

Most Common- High risk of bleeding in gastrointestinal tract, abdominal tract, brain (hemorrhagic stroke), skin and chest cavity.
Blood- Decrease in the platelet count.
Genitourinary- Renal failure, blood in urine.