- Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial - (https://pubmed.ncbi.nlm.nih.gov/16801576/ )
- Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy - (https://pubmed.ncbi.nlm.nih.gov/18447661/)
- Epalrestat. A review of its pharmacology, and therapeutic potential in late-onset complications of diabetes mellitus - (https://pubmed.ncbi.nlm.nih.gov/8312678/ )
- Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771994/)
Epalrestat Medication Information
Get detailed information on Epalrestat, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Epalrestat provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Epalrestat Pronunciation : Ep-al-re-stat Therapeutic Classification : AntidiabeticsTrade Names/Brand Names of Epalrestat
India :
Overview of Epalrestat
• Epalrestat is used for the treatment of nerve damage in diabetes patients.Why is Epalrestat Prescribed? (Indications)
Epalrestat is used for the treatment of nerve damage due to diabetes called diabetes neuropathy.It inhibits the enzyme aldose reductase and reduces the level of sorbitol, which damages the nerves.
When should Epalrestat not be taken? (Contraindications)
• Epalrestat is contraindicated in patient with allergies and severe liver disease.What is the dosage of Epalrestat?
• The recommended dose of epalrestat is 50 mg tablet taken orally three times a day before meals.How should Epalrestat be taken?
• Epalrestat should be ideally taken before meals.What are the warnings and precautions for Epalrestat?
• Caution is advised in cases of kidney impairment.What are the side effects of Epalrestat?
Gastrointestinal disorder: Nausea, vomiting, diarrheaSkin: Redness, rash, and skin blistering
Liver: Increase in liver enzymes
Kidney: Kidney dysfunction, edema
Nervous system: Dizziness, drowsiness, headache
Others: High blood pressure
What are the other precautions for Epalrestat?
• Do not take if you are pregnant, breastfeeding or planning to become pregnant unless you consult your doctor.• Do not use heavy machinery or drive while taking the drug due to possible dizziness and drowsiness.
