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Epoprostenol - Indications, Dosage, Side Effects and Precautions

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Epoprostenol Medication Information

Get detailed information on Epoprostenol, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Epoprostenol provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Epoprostenol
Pronunciation : E-poe-PROST-e-nol
ICD Code : Y52.7 Therapeutic Classification : Anti- Hypertensives

Trade Names/Brand Names of Epoprostenol

International :


Flolan and Veletri

Why is Epoprostenol Prescribed? (Indications)

This medication is a prostaglandin, prescribed for pulmonary arterial hypertension. The medication relaxes blood vessels.

When should Epoprostenol not be taken? (Contraindications)

Contraindicated in people with congestive heart failure, lung swelling and hypersensitivity.

What is the dosage of Epoprostenol?

IV- The initial recommended dose is 2 mg/kg/min and increased in increments of 2 mg/kg/min every 15 minutes.

How should Epoprostenol be taken?

It comes as a solution for injection to be administered by a healthcare provider.

What are the warnings and precautions for Epoprostenol?

• Caution should be exercised in patients with history of bleeding problem, heart failure, liver or kidney, blood disorders, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness, and lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

What are the side effects of Epoprostenol?

Most Common- Chest pain, anxiety, dizziness, slow or fast heart rate, difficulty in breathing, abdominal pain and musculoskeletal pain.
General- Weakness, fever, chills, flushing and flu-like symptoms.
Heart- Paleness, bluish color of the skin, palpitations, stroke, shock, bleeding, low blood pressure and heart attack.
Gastrointestinal- Loss of appetite, excess fluid, constipation, nausea, vomiting and flatulence.
Metabolic- Swelling in the leg, decreased potassium level in blood and weight loss/gain.
Musculoskeletal- Joint/bone/jaw pain.
Central Nervous System- Confusion, convulsion, depression, sleeplessness and headache.
Respiratory- Increased cough, nosebleed, excess fluid and inflammation of sinus.
Skin- Itching, rash, sweating, skin ulcer and hives.
Eye- Lazy eye and vision abnormality.
Genitourinary- Urinary tract infection and blood in urine.

What are the other precautions for Epoprostenol?

Avoid alcohol consumption.

What are the storage conditions for Epoprostenol?

Store reconstituted solutions in refrigerator at 2° to 8°C; avoid exposure to sunlight.

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