Medindia LOGIN REGISTER
Medindia

Eptifibatide - Indications, Dosage, Side Effects and Precautions

Advertisement

Eptifibatide Medication Information

Get detailed information on Eptifibatide, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Eptifibatide provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Eptifibatide
Pronunciation : ep-ti-FIB-ih-tide
ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Eptifibatide

India :

International :


Integrilin

Why is Eptifibatide Prescribed? (Indications)

This medication is an antithrombotic agent, prescribed for the treatment of patients with acute coronary syndrome (heart condition), and those undergoing percutaneous coronary intervention (angioplasty), and stenting (placing of a cylindrical device within vessels). It prevents platelets in the blood from sticking to each other.

When should Eptifibatide not be taken? (Contraindications)

Contraindicated in patients with increased risk of bleeding disorders, brain disorders, history of stroke, uncontrolled hypertension, severe injury, severe kidney impairment, recent major surgery, breastfeeding.

What is the dosage of Eptifibatide?

Intravenous- Unstable angina(acute coronary syndrome)- Adult: 180 mcg/kg via IV injection followed by 2 mcg/kg/minute by IV infusion for up to 72 hours. If percutaneous coronary intervention is performed during therapy, infusion should be continued for 18-24 hours after procedure, up to a max total duration of 96 hours of therapy.

How should Eptifibatide be taken?

It will be administered as an injection at a hospital.

What are the warnings and precautions for Eptifibatide?

•Discontinue in case of serious uncontrolled bleeding, or if emergency surgery or thrombolytic (drugs are used in medicine to dissolve blood clots) therapy is required.

Caution should be exercised in patients with liver impairment, platelet counts <100,000 mm3; bleeding in the eye, drugs affecting blood, pregnancy.

Check aPTT [activated partial thromboplastin time or ACT(activated clotting time) prior to sheath removal during angioplasty.

It may lead to severe kidney impairment, inflammation of blood vessels, bleeding in the eye, acute pericardial inflammation ( inflammation of the covering of the heart)or aortic dissection (splitting of the layers of the aorta leading to formation of outpouchings).

What are the side effects of Eptifibatide?

Allergic Reactions- Easy bruising or bleeding, pink or red-colored urine, black stool, coffee-ground vomit, one-sided weakness, vision problems, confusion, slurred speech.
Heart- Low blood pressure.
Blood- Reduced platelets, cerebral, GI, and lung bleeding, acute profound thrombocytopenia, fatal bleeding events.
Local- Overall incidence of major bleeding, major bleeding.

What are the other precautions for Eptifibatide?

Monitor complete blood counts, serum creatinine levels regularly.

What are the storage conditions for Eptifibatide?

Storage: Store at 25 °C. Store it in airtight container and keep away from children.

Advertisement