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Ethionamide - Indications, Dosage, Side Effects and Precautions

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Ethionamide Medication Information

Discover comprehensive details about Ethionamide, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Ethionamide brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Ethionamide
Pronunciation : ETH-eye-ON-a-mide
ICD Code : Y41.1 Therapeutic Classification : Anti- Tuberculosis

Brand Names or Trade Names of Ethionamide

India :

Overview of Ethionamide

• Ethionamide is an antibiotic which is used for the treatment of tuberculosis.

Why is Ethionamide Prescribed? (Indications)

Ethionamide is an antibiotic. It is used for the treatment of tuberculosis as a second-line drug in combination with other drugs, especially in cases of resistance to the standard drugs.

When should Ethionamide not be taken? (Contraindications)

• It is contraindicated in patients allergic to drugs or with severe liver impairment.
• It should not be used in porphyria.

What is the dosage of Ethionamide?

• The recommended adult dose for ethionamide is 5 to 20 mg/kg tablet.
• Start with a low dose and increase over every one to two days to a maximum dose of 1 g/day.

How should Ethionamide be taken?

• Ethionamide should be taken once daily or in divided doses after the meal as directed by the physician.

What are the warnings and precautions for Ethionamide?

• Caution should be taken in patients with diabetes mellitus or kidney disease

• Liver function tests and eye examinations should be conducted on a regular basis during treatment

• Caution should be taken in patients with thyroid dysfunction.

What are the side effects of Ethionamide?

Digestive system: Nausea, vomiting, diarrhea, abdominal pain, stomatitis, loss of appetite
Nervous System: Drowsiness, dizziness, restlessness, psychiatric disturbances, peripheral neuropathy, headache and seizure
Eye: Blurring of vision, double vision, optic neuropathy
Liver: Hepatitis, jaundice
Cardiovascular: Low blood pressure
Others: Skin reactions, impotence, reduced white blood cell and platelet counts, allergic reactions, joint pain

What are the other precautions for Ethionamide?

• Do not use the drug during pregnancy.
• It is important to complete the course of the tuberculosis medicines even if the patient is feeling well.

What are the Drug Interactions of Ethionamide?

• Alcohol may enhance the adverse effect of ethionamide resulting in a psychotic episode.
• Ethionamide should not be taken in combination with cholera or other live vaccines as the antibiotic may diminish the therapeutic effects of the vaccines.
• Ethionamide may increase the side effect of cycloserine.
• Ethionamide may increase the blood level of isoniazid.

What are the storage conditions for Ethionamide?

• It should be stored Store at 20°C to 25°C.

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