Ezetimibe and Simvastatin Medication Information

Learn everything you need to know about Ezetimibe and Simvastatin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Ezetimibe and Simvastatin brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Ezetimibe and Simvastatin

Pronunciation : e-ZET-i-mibe - SIM-va-STAT-in

ICD Code : Y52.6 Therapeutic Classification : Antilipemics

Brand Names or Trade Names of Ezetimibe and Simvastatin

International :

Vytorin

Why is Ezetimibe and Simvastatin Prescribed? (Indications)

This combination medication contains an antihyperlipidemic agent and an HMG-CoA reductase inhibitor, prescribed for high cholesterol with diet.

When should Ezetimibe and Simvastatin not be taken? (Contraindications)

♦ Contraindicated in patients with liver enzyme abnormalities, during pregnancy and breastfeeding, and hypersensitivity.
It should not be co-administered with CYP3A4 inhibitors.

What is the dosage of Ezetimibe and Simvastatin?

Adult- PO- The recommended usual starting dose is 10/20 mg/day. The dosage range is 10/10 mg/day through 10/80 mg/day.

How should Ezetimibe and Simvastatin be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Ezetimibe and Simvastatin?

• Caution should be exercised in patients with history of low blood pressure, sugar, thyroid deficiency, muscle cramps, hormonal, or electrolyte problems, seizures, kidney, or liver disease, alcohol abuse, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness or changes in vision, do not drive a car or operate machinery while taking this medication.

• Proper dental care is needed while taking this medication.

• Monitor blood cholesterol levels, liver function, and creatine phosphokinase (CPK) blood level regularly while taking this medication.

What are the side effects of Ezetimibe and Simvastatin?

Body as a whole - Headache.
Gastrointestinal - Diarrhea, abdominal pain, constipation, indigestion, flatulence and stomach inflammation.
Respiratory - Influenza and upper respiratory tract infection.
♦ Musculoskeletal - Muscle pain, pain in extremities and Immune-mediated Necrotizing Myopathy (IMNM).
ENT - Inner ear damage.
Skin - Skin inflammation and rash.
Genitourinary - Increased sugar and urinary tract infections.
Body as a whole - Weakness and swelling.
Central Nervous System - Sleeplessness.