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Glucarpidase Injection - Indications, Dosage, Side Effects and Precautions

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Glucarpidase Injection Medication Information

Discover comprehensive details about Glucarpidase Injection, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Glucarpidase Injection brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Glucarpidase Injection
ICD Code : Y43.6 Therapeutic Classification : Enzymes

Brand Names or Trade Names of Glucarpidase Injection

International :


Voraxaze

Why is Glucarpidase Injection Prescribed? (Indications)

This medication is a carboxypeptidase enzyme, prescribed for reducing methotrexate toxic level in kidney failure patients. It converts methotrexate into an inactive substance.

When should Glucarpidase Injection not be taken? (Contraindications)

None.

What is the dosage of Glucarpidase Injection?

IV- The recommended dose is 50 Units per kg as a single dose.

How should Glucarpidase Injection be taken?

It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Glucarpidase Injection?

• Caution should be exercised in patients with history of liver or kidney impairment, any allergy, elderly, children, during pregnancy and breastfeeding.

What are the side effects of Glucarpidase Injection?

Tingling, flushing, nausea, vomiting, headache, low blood pressure, blurred vision, diarrhea, hypersensitivity, high blood pressure, rash, throat irritation.

What are the other precautions for Glucarpidase Injection?

Avoid excess dosage.

What are the storage conditions for Glucarpidase Injection?

• Store in a refrigerator at a controlled temperature between 2°C and 8°C.
• Vials should not be frozen

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